West China Journal of Stomatology ›› 2022, Vol. 40 ›› Issue (6): 690-697.doi: 10.7518/hxkq.2022.06.010

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Treatment of multiple adjacent gingival recessions with an acellular dermal matrix or a connective tissue graft: a Meta-analysis

Cong Zhaoxia1(), Liu Yuan1, Zhao Jin1,2()   

  1. 1.Dept. of Endodontics, The First Affiliated Hospital of Xin-;jiang Medical University, Urumqi 830000, China
    2.Xinjiang Oral Medical Research Institute, Urumqi 830000, China
  • Received:2022-05-19 Revised:2022-09-23 Online:2022-12-01 Published:2022-11-23
  • Contact: Zhao Jin E-mail:1154615126@qq.com;merryljin@sina.com


Objective To evaluate the effectiveness of an acellular dermal matrix or a connective tissue autograft in the treatment of multiple adjacent gingival recessions through Meta-analysis. Methods Randomized controlled trials were screened in four electronic databases in English according to the inclusion and exclusion criteria until April 20, 2022. The main outcome indicators were keratinized gingival tissue width, recession depth, probing depth, clinical attachment level, complete root coverage, and root coverage esthetic score. Results Seven randomized controlled trials were included. After 12 months, the connective tissue graft in the control group could increase the keratinized gingival tissue width [mean difference (MD)=-0.28 (-0.47, -0.08), P=0.006], reduce the gingival recession depth [MD=0.23 (0.12, 0.35), P<0.000 1], and improve the complete root coverage [risk ratio=0.80, 95% confidence interval (0.69, 0.93), P=0.003] compared with the acellular dermal matrix in the experimental group. No significant difference was found in probing depth, clinical attachment level, and root coverage esthetic score between groups. Conclusion Connective tissue grafts have advantages in increasing the keratinized gingival tissue width, reducing the gingival recession depth, and improving the complete root coverage in surgeries for treating multiple adjacent gingival recessions. Acellular dermal matrices also have some clinical value in terms of operation simplicity and similar effectiveness.

Key words: multiple adjacent gingival recessions, connective tissue graft, acellular dermal matrix, Meta-analysis

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