1例药物诱发天疱疮的诊治体会

doi:10.7518/hxkq.2021.06.016

华西口腔医学杂志 ›› 2021, Vol. 39 ›› Issue (6): 724-727.doi: 10.7518/hxkq.2021.06.016

1例药物诱发天疱疮的诊治体会

袁培养¹(), 邱敏¹^,², 万梓欣³, 江潞¹()

^1.口腔疾病研究国家重点实验室国家口腔疾病临床医学研究中心四川大学华西口腔医院黏膜病科，成都? 610041
^2.深圳市人民医院口腔医学中心口腔内科，深圳 518020
^3.口腔疾病研究国家重点实验室国家口腔疾病临床医学研究中心四川大学华西口腔医院病理科，成都? 610041

收稿日期:2020-09-11 修回日期:2021-05-18 出版日期:2021-12-01 发布日期:2021-12-03
通讯作者: 江潞 E-mail:yuanpeiyangvip@163.com;jianglu@scu.edu.cn
作者简介:袁培养，硕士，E-mail：yuanpeiyangvip@163.com
基金资助:
国家自然科学基金(81670998)

Experience in the diagnosis and treatment of a drug-induced pemphigus

Yuan Peiyang¹(), Qiu Min¹^,², Wan Zixin³, Jiang Lu¹()

^1.State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
^2.Dept. of Oral Medicine, Stomatology Center, Shenzhen People, s Hospital, Shenzhen 518020, China
^3.State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Oral Pathology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China

Received:2020-09-11 Revised:2021-05-18 Online:2021-12-01 Published:2021-12-03
Contact: Jiang Lu E-mail:yuanpeiyangvip@163.com;jianglu@scu.edu.cn
Supported by:
The National Natural Science Foundation of China(81670998)

摘要/Abstract

摘要：

药物诱发天疱疮（DIP）是天疱疮的一种特殊类型，其发病机制及治疗预后特点与其诱发药物密切相关。本文报道1例结核病患者服用利福平导致DIP（寻常型天疱疮）的诊治经过，并结合文献讨论DIP的类型、发病机制、鉴别诊断与治疗原则，建议在口腔临床实践中对诊断为寻常型天疱疮的患者应特别强调排查DIP的可能性。

关键词: 药物诱发天疱疮, 利福平, 寻常型天疱疮, 结核病

Abstract:

Drug-induced pemphigus (DIP) is a special type of pemphigus, and its pathogenesis, characteristics of treatment, and prognosis are closely related to the inducing drugs. This article reports the diagnosis and treatment of DIP (pemphigus vulgaris) caused by the administration of rifampin to a patient with tuberculosis. Combined with the literature, we discussed the types, pathogenesis, differential diagnosis, and treatment principles of DIP. We propose that in the oral clinical practice for patients with pemphigus vulgaris, the importance of investigating suspected drugs that induce DIP should be emphasized.

Key words: drug-induced pemphigus, rifampin, pemphigus vulgaris, tuberculosis

中图分类号:

R 781.5

袁培养, 邱敏, 万梓欣, 江潞. 1例药物诱发天疱疮的诊治体会[J]. 华西口腔医学杂志, 2021, 39(6): 724-727.

Yuan Peiyang, Qiu Min, Wan Zixin, Jiang Lu. Experience in the diagnosis and treatment of a drug-induced pemphigus[J]. West China Journal of Stomatology, 2021, 39(6): 724-727.

图/表 2

参考文献 22

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1例药物诱发天疱疮的诊治体会

Experience in the diagnosis and treatment of a drug-induced pemphigus

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