Relationship between fluid shear stress in alveolar bone under orthodontic forces and bone remodeling rate

doi:10.7518/hxkq.2025.2024288

Abstract

Abstract:

Objective This study explores the differences in fluid flow within alveolar cancellous bone at various sites under orthodontic forces and elucidates the relationship between fluid shear stress and bone remodeling. These fin-dings lay the groundwork for understanding the biomechanical mechanisms of orthodontic tooth movement. Methods Stress relaxation tests were performed on human alveolar bone samples to determine material parameters by using the Prony series. An inverse model of alveolar bone was then developed for numerical simulations of fluid-structure interactions to calculate fluid flow within cancellous bone. Meanwhile, a rat model of tooth movement was established to investigate variations in bone remodeling speeds across different regions. Results The microstructural distribution of cancellous alveolar bone was similar in humans and rats. The bone volume fraction and trabecular thickness gradually decreased from root cervical region to root apical region, while the trabecular space gradually increased. Under the influence of orthodontic forces, fluid shear stress within cancellous bone showed spatial variability across different levels, with the highest shear stress occurring at the root apical region, ranging from 0 to 0.936 6 Pa. Additionally, the rat model of tooth movement indicated that bone remodeling occurred more rapidly at the root apical region. Conclusion Fluid stimulation has a remarkable effect on al-veolar bone remodeling, causing changes in the structure of alveolar bone and ultimately regulating the speed of structu-ral remodeling.

Key words: alveolar bone, fluid-structure interaction, fluid shear stress, porous structure

CLC Number:

R783.5

Wu Bin, Hu Kexin, Yang Fan, Lu Yi, Jiang Di, Yi Yang, Yan Bin. Relationship between fluid shear stress in alveolar bone under orthodontic forces and bone remodeling rate[J]. West China Journal of Stomatology, 2025, 43(2): 190-196.

Figures/Tables 9

Fig 1

Fig 2

Tab 1

Fig 3

Tab 2

Prony series parameters

部位	$g 1$	$τ 1$	$g 2$	$τ 2$	$g 3$	$τ 3$	$g 4$	$τ 4$
根颈	0.002?25	0.202?31	0.002?49	5.647?00	0.002?53	5.746?10	0.006?52	115.976?14
根中	0.004?21	0.347?41	0.005?22	3.037?46	0.006?79	18.824?24	0.011?82	142.652?27
根尖	0.003?77	0.521?32	0.006?57	3.889?65	0.007?09	20.039?15	0.011?84	168.032?36

Tab 2

Fig 4

Tab 3

Optimization of inversion parameters

部位	$g 1$	$τ 1$	$g 2$	$τ 2$	$g 3$	$τ 3$	$g 4$	$τ 4$
根颈	0.002?47	0.347?41	0.003?38	3.037?50	0.003?61	17.942?00	0.008?62	128.530?00
根中	0.004?72	0.436?79	0.005?48	5.873?94	0.007?63	23.375?93	0.014?96	153.924?95
根尖	0.003?46	0.475?32	0.005?85	7.834?65	0.008?58	34.543?27	0.014?79	174.548?69

Tab 3

Fig 5

Fig 6

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部位	BV/TV/%	Tb.Sp/μm	Tb.Th/μm
根颈	31.745±0.624	8.409±0.527	15.654±0.465
根中	27.364±0.317	10.267±0.223	13.193±0.752
根尖	23.989±0.462	12.414±0.625	11.988±0.659

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