West China Journal of Stomatology ›› 2019, Vol. 37 ›› Issue (6): 656-659.doi: 10.7518/hxkq.2019.06.015

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Research progress on the pathogenesis of inflammatory external root resorption

Wu Jiayi,Li Xin,Wang Chenglin,Ye Ling,Yang Jing   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2019-03-12 Revised:2019-06-19 Online:2019-12-01 Published:2019-11-27
  • Supported by:
    The National Natural Science Foundation of China(81600859);Sci-tech Innovation Seedling Project of Science and Technology Department of Sichuan Province([17-YCG053(2017036)])

Abstract:

Inflammatory external root resorption (IERR) refers to the pathological process of dissolving the hard tissue on the outer surface of the tooth root by the body’s own immune system under the stimulation of various physical and chemical factors such as infection, stress, trauma and orthodontic treatment. Severe IERR can lead to endodontic and periodontal diseases, and even the loss of teeth. Therefore, understanding the etiology and the pathogenic mechanism of IERR are of importance in its prevention and treatment. This article will review the etiology and the regulation mechanisms of IERR.

Key words: inflammatory external root resorption, cementum, pathogenesis

CLC Number: