华西口腔医学杂志

• 病例报告 • 上一篇    下一篇

安氏Ⅱ类一家系分析

张晓歌1 杨帆2 陈琳3 陈嵩1 陈扬熙1   

  1. 1.四川大学华西口腔医院正畸科;2.四川大学华西医院生物治疗国家重点实验室人类疾病相关多肽研究室, 四川成都610041;3.四川石油总医院中西医结合科, 四川成都610213
  • 收稿日期:2010-04-25 修回日期:2010-04-25 出版日期:2010-04-20 发布日期:2010-04-20
  • 通讯作者: 陈扬熙,Tel:028-85503477
  • 作者简介:张晓歌(1975—),男,河南人,主治医师,博士

Angle′s Class Ⅱ malocclusion: A report of seven cases in one family

ZHANG Xiao-ge1, YANG Fan2, CHEN Lin3, CHEN Song1, CHEN Yang-xi1   

  1. 1. Dept. of Orthodontics, West China College of Stomatology, Sichuan University, Chengdu 610041, China; 2. Division of Peptides Related with Human Diseases, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China; 3. Dept. of Integrated Traditional and Western Medicine, Sichuan Petroleum General Hospital, Chengdu 610213, China
  • Received:2010-04-25 Revised:2010-04-25 Online:2010-04-20 Published:2010-04-20
  • Contact: CHEN Yang-xi,Tel:028-85503477

摘要:

安氏Ⅱ类在临床上较常见,但关于安氏Ⅱ类家系的报道较为少见。四川大学华西口腔医院正畸科发现1例安氏Ⅱ类一家系(7例患者),并对其进行家系调查和系谱分析。

关键词: 错畸形, 安氏Ⅱ类, 系谱, 基因

Abstract:

A family with Angle′s Class Ⅱ malocclusion was identified in West China Stomatological Hospital of Sichuan University. The proband was a 22 -year -old woman with Angle′ s Class Ⅱ Division 2 malocclusion with congenitally missing teeth. A total of 15 members of the 3 generations in the family were investigated. There were 7 members(3 males, 4 females) with Angle′s Class Ⅱ malocclusion in the family. The results provide the primary basis for further study to localize the virulence gene.

Key words: malocclusion, Angle′s Class Ⅱ, pedigree, gene