华西口腔医学杂志

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口腔转化医学

郑黎薇 王琪 周学东   

  1. 口腔疾病研究国家重点实验室, 四川大学, 成都610041
  • 收稿日期:2011-06-25 修回日期:2011-06-25 出版日期:2011-06-20 发布日期:2011-06-20
  • 通讯作者: 周学东,Tel:028-85501481
  • 作者简介:郑黎薇(1982—),女,四川人,博士

Translational dental medicine

ZHENG Li-wei, WANG Qi, ZHOU Xue-dong   

  1. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China
  • Received:2011-06-25 Revised:2011-06-25 Online:2011-06-20 Published:2011-06-20
  • Contact: ZHOU Xue-dong,Tel:028-85501481

摘要:

随着科学技术手段的飞速发展,大量累计的基础科研成果迫切需要转化为临床应用,这催生了新的医学研究领域———转化医学。转化医学是指对实验所得的新型检测手段或治疗方法在人体上进行可行性地验证及转化,同时其含义涵盖了以病患需求为中心的人口研究,并探索怎样将研究结果有效地运用于公共卫生领域。转化医学是近年来最炙手可热的研究领域,实现转化医学对提高人群生存质量、更新重大疾病的研究思路与技术具有重要意义,然而转化医学研究的实施却面临了诸多困难。本文在此对转化医学的产生背景、概念、口腔转化医学研究现状、基本要素及面临的困难作一综述。

关键词: 转化医学, 口腔医学, 口腔转化医学, 概念, 背景, 现状, 基本要素

Abstract:

Over the last decade, as tremendous innovations have been achieved in scientific technology, translational medicine has come into the focus of academic medicine, and significant intellectual and financial efforts have been made to initiate a multitude of bench-to-bedside projects. The concept of translational medicine is described as the transfer of new understandings of disease mechanisms gained in the laboratory into the development of new methods for diagnosis, therapy, and prevention and their first testing in humans, meanwhile, translational medicine also is described as a patient- oriented population research and the translation of results from clinical studies into everyday clinical practice and health decision making. Translational medicine is a hot spot in recent academic field, and it is crucial for improving the living standard of population and renewing the research idea and technology. It has, however, significant obstacles during the approach of translational medicine. We here review the background, concept, current situation of translational dental medicine, key components and obstacles of translational medicine.

Key words: translational medicine, dentistry, translational dental medicine, concept, background, current situation, key component