华西口腔医学杂志

• 临床研究 • 上一篇    下一篇

急性根尖周炎患牙治疗前后前列腺素E-2水平的变化

刘卫红,于金华,周洪波,郑仕中   

  1. 210029 南京医科大学附属口腔医院口腔内科(刘卫红,于金华),南京医科大学同位素教研室(周洪波,郑仕中)
  • 收稿日期:2003-02-25 修回日期:2003-02-25 出版日期:2003-02-20 发布日期:2003-02-20

Changes of Prostaglandin E2Levels in Periapical Exudates after Root Canal Treatment

LIUWeihong*,YUJinhua,ZHOUHongbo,et al.   

  1. *Department ofEndodontics,Stomatological College,NanjingMedical Uni- versity,Nanjing210029,China
  • Received:2003-02-25 Revised:2003-02-25 Online:2003-02-20 Published:2003-02-20

摘要:

目的 检测急性根尖周炎患牙治疗前后根管渗出液中前列腺素E2水平的变化。方法 用同位素放射免疫法测定25例急性根尖周炎患牙治疗前后根管内渗出液中前列腺素E2含量的变化。结果 急性根尖周炎患牙治疗前后前列腺素E2的含量明显不同,治疗前明显高于治疗后。结论 前列腺素E2水平的变化与根尖周炎临床表现之间有着密切的关系,根管渗出液中前列腺素E2浓度反映出根尖周炎的活动性。

关键词: 前列腺素, 根尖周炎, 根管治疗

Abstract:

Objective The aim of this study was to examine the levels of prostaglandin E2in periapical exudates before and after root canal treatment.Methods Periapical exudates specimens were quantitatively sampled from root canals of 25 teeth at con- secutive treatment visits, and the concentration of prostaglandin E2in each sample was determined using a commercial kit.Results  The mean prostaglandin E2levels significantly decreased after the endodontic therapy. Significant correlations between the levels of prostaglandin E2and the clinical features of periapical periodontitis were also found in this study.Conclusion The results suggest that the level of prostaglandin E2in periapical exudates reflects the state of periapical periodontitis.

Key words: prostaglandin, periapical periodontitis, root canal treatment