Abstract:

Objective　Clinical effects in local application of hyaluronic acid (HA) adjunctive to scaling and root planing (SRP) were evaluated.Methods　In this cross over design study 20 patientswith chronic periodontitiswere included. Plaque in- dex, sulcus-fluid-flow-rate (SFFR), sulcus bleeding index, probing pocket depth and attachment level were monitored. All pa- tients were treated with full mouth SRP, in addition a HA gel was administered subgingivally in the test site every week for 6 weeks.Results　A statistically significant improvement of all clinical test parameters was observed in both groups (P<0·05). Clinically, no significant difference between test and control group could be found. However, the SFFR decreased significantly faster in the test group.Conclusion　No post-inflammatory tissue regeneration could be achieved by the adjunctive use ofHAgel to SRP in the patients with chronic periodontitis. Due to SFFR a control of local inflammation can be achieved quickly.

Key words: hyaluronic acid, chronic periodontitis, scaling and root planing