West China Journal of Stomatology ›› 2021, Vol. 39 ›› Issue (2): 195-202.doi: 10.7518/hxkq.2021.02.011
Guo Jincai1(), Xie Hui1(
), Wu Hao1, Tong Tiejun2
Received:
2020-07-17
Revised:
2020-11-14
Online:
2021-04-01
Published:
2021-04-09
Contact:
Xie Hui
E-mail:540009728@qq.com;kqyyxh1@126.com
Supported by:
CLC Number:
Guo Jincai, Xie Hui, Wu Hao, Tong Tiejun. Efficacy of curcumin in the treatment of oral submucous fibrosis: a Meta-analysis[J]. West China Journal of Stomatology, 2021, 39(2): 195-202.
Tab 1
The search strategy of PubMed
步骤 | 检索策略 |
---|---|
1 | “Oral submucous fibrosis”[MeSH] OR “OSF” [MeSH] OR “OSMF” [MeSH] |
2 | “Atrophia idiopathica mucosae oris” [Title/Abstract] OR “Diffuse oral submucous fibrosis” [Title/Abstract] OR “Submucous fibrosis of the palate and pillars” OR “Idiopathic scleroderma of the mouth” [Title/Abstract] OR “Asian side-ropenic dysphagia” [Title/Abstract] OR “Sclerosing stomatitis” [Title/Abstract] OR “Idiopathic palatal fibrosis” [Title/Abstract] OR “Juxta-epithelial fibrosis” [Title/Abstract] |
3 | 1 OR 2 |
4 | “Curcumin” [Title/Abstract] OR “Turmeric” [Title/Abstract] |
5 | 3 AND 4 |
Tab 2
Characteristics of included studies
纳入 研究 | 例数 (T/C) | 年龄/岁 | 性别(男/女) | 干预措施 | 疗程/月 | 随访 时间/月 | 结局 指标 | |||
---|---|---|---|---|---|---|---|---|---|---|
T | C | |||||||||
Piyush 等[ | 30/30 | 17~60(32) | 53/7 | 姜黄素300 mg, po,bid | 番茄红素8 mg,po, bid | 6 | 3 | ①② ③④ | ||
Saran 等[ | 30/30 | T:27.9±8.66 | C:26.00±6.43 | T:21/9 | C:19/11 | 姜黄素300 mg, po,tid | 番茄红素4 mg,po, bid | 3 | 1 | ①② |
Ara 等[ | 50/50 | T:25.42±7.38 | C:25.44±5.43 | T:45/5 | C:48/2 | 姜黄素500 mg, po,bid | 安慰剂500 mg,po, bid | 6 | 0 | ①② ③④ |
Kopuri 等[ | 15/15 | 不详 | 不详 | 姜黄素400 mg, po,bid | 番茄红素4mg,po, bid | 3 | 0 | ①② ⑤⑥ | ||
Hazarey等[ | 15/15 | 18~50 | 不详 | 姜黄素400 mg, po,tid | 局部涂氯倍他索乳膏, tid | 3 | 6 | ①② | ||
Yadav等[ | 20/20 | T:37.9±10.5 | C:37.9±10.5 | T:15/5 | C:16/4 | 姜黄素300 mg, po,qd | 地塞米松4 mg+透明质 酸酶1 500 IU局部注射, 1周1次 | 3 | 3 | ①④ |
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