West China Journal of Stomatology ›› 2020, Vol. 38 ›› Issue (4): 460-463.doi: 10.7518/hxkq.2020.04.019

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Bisphosphonate-related osteonecrosis of the jaw caused by implant: a case report

Wu Pingfan(), Li Yu, Lei Zhenge, Chen Linlin()   

  1. Affiliated Stomatological Hospital of Nanchang University, The Key Laboratory of Biomedicine of Jiangxi Province, Nanchang 330006, China
  • Received:2019-08-25 Revised:2020-03-19 Online:2020-08-01 Published:2020-08-03
  • Contact: Chen Linlin E-mail:oral_surgery@sina.com
  • Supported by:
    Science and Technology Plan of Health Commission of Jiangxi Province(20171096)


Osteonecrosis of the jaw could occur after intake of bisphosphonate drugs, which are widely used to treat osteoporosis and bone metastasis of malignant tumors. This effect has aroused concern among dentists. In this paper, a case of bisphosphonate-related osteonecrosis caused by implant is reported, and the pathogenesis, diagnosis, prevention, and treatment of bisphosphonate drug-induced osteonecrosis are described through a literature review. The effects of bisphosphonate drug treatment on dental implants are also discussed.

Key words: bisphosphonate, osteonecrosis, jaw, implant

CLC Number: