口腔扁平苔藓基因多态性的研究

doi:10.7518/hxkq.2020.06.013

华西口腔医学杂志 ›› 2020, Vol. 38 ›› Issue (6): 681-686.doi: 10.7518/hxkq.2020.06.013

口腔扁平苔藓基因多态性的研究

潘英潇(), 郭大伟, 李新, 刘恒毅, 卢恕来()

青岛大学口腔医学院青岛大学附属青岛市市立医院口腔医疗中心,青岛 266000

收稿日期:2019-04-07 修回日期:2020-06-29 出版日期:2020-12-01 发布日期:2020-12-07
通讯作者: 卢恕来 E-mail:panyingxiao01@163.com;lshl97@163.com
作者简介:潘英潇,硕士,E-mail：panyingxiao01@163.com
基金资助:
青岛市科技计划项目(17-3-3-39-nsh);山东省医药卫生科技发展计划项目面上项目(2015WS0327);山东省卫计委中医药科技发展计划项目(2015-378)

Gene polymorphism in oral lichen planus

Pan Yingxiao(), Guo Dawei, Li Xin, Liu Hengyi, Lu Shulai()

Dept. of Stomatology, Qingdao University & Dept. of Stomatology, Affiliated Qingdao Municipal Hospital, Qingdao University, Qigndao 266000, China

Received:2019-04-07 Revised:2020-06-29 Online:2020-12-01 Published:2020-12-07
Contact: Lu Shulai E-mail:panyingxiao01@163.com;lshl97@163.com
Supported by:
Qingdao Science and Technology Project(17-3-3-39-nsh);General Program of Medical Health Science and Technology Development Project of Shandong Province(2015WS0327);Science and Technology Development Project of Traditional Chinese Medicine of Shandong Provincial Health Commission(2015-378)

摘要/Abstract

摘要：

口腔扁平苔藓（OLP）是一种常见的口腔黏膜慢性炎症性疾病,成年人患病率为0.5%~2%。OLP的病因和发病机制尚不明确,研究显示其发病可能与某些基因的遗传多态性相关,目前研究较多的有肿瘤坏死因子、干扰素、白细胞介素、酶类、受体等基因家族。本文就基因多态性与口腔扁平苔藓的相关性进行综述。

关键词: 口腔扁平苔藓, 基因多态性, 遗传, 病因

Abstract:

Oral lichen planus (OLP) is a common chronic inflammatory disease of the oral mucosa. The prevalence rate of OLP in adults is 0.5%-2%. The etiology and pathogenesis of OLP are still unclear. The pathogenesis of OLP may be related to the genetic polymorphism of some genes. Currently, the gene families, including tumor necrosis factor, interferon, interleukin, enzyme, and receptor, have been extensively studied. This work reviews related studies on gene polymorphism of OLP.

Key words: oral lichen planus, gene polymorphism, genetics, etiology

中图分类号:

R781.5

潘英潇, 郭大伟, 李新, 刘恒毅, 卢恕来. 口腔扁平苔藓基因多态性的研究[J]. 华西口腔医学杂志, 2020, 38(6): 681-686.

Pan Yingxiao, Guo Dawei, Li Xin, Liu Hengyi, Lu Shulai. Gene polymorphism in oral lichen planus[J]. West China Journal of Stomatology, 2020, 38(6): 681-686.

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口腔扁平苔藓基因多态性的研究

Gene polymorphism in oral lichen planus

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