牙周病与常见恶性肿瘤关系的研究进展

doi:10.7518/hxkq.2019.03.018

摘要/Abstract

摘要：

牙周病作为口腔最常见疾病之一,可造成牙周支持组织的不可逆破坏。近年来,关于牙周病与恶性肿瘤相关性的研究日益增多。本文就牙周病与消化道恶性肿瘤（胃癌、结直肠癌、胰腺癌）、肺癌、乳腺癌三类常见恶性肿瘤的相关性进行讨论,并从免疫、炎症、基因、微生物及其产物等方面总结相关机制,为恶性肿瘤的预防和早期诊断提供新思路。

关键词: 牙周病, 消化道恶性肿瘤, 肺癌, 乳腺癌

Abstract:

Periodontal disease is a common oral disease that can cause irreversible damage of periodontal support tissue. Studies on the relationship between periodontal disease and malignancies have also increased. In this review, the relationship between periodontal disease and gastrointestinal malignancies (e.g., stomach cancer, colorectal cancer, and pancreatic cancer), lung cancer, and breast cancer are discussed. The related mechanisms are summarized in terms of four aspects, namely, immunity, inflammation, gene, and microbiota and its products, to provide novel methods for the prevention and early diagnosis of malignancies.

Key words: periodontal disease, gastrointestinal malignancies, lung cancer, breast cancer

中图分类号:

R781.4

郝渝,彭显,周学东,程磊. 牙周病与常见恶性肿瘤关系的研究进展[J]. 华西口腔医学杂志, 2019, 37(3): 320-324.

Yu Hao,Xian Peng,Xuedong Zhou,Lei Cheng. Research progress on the relationship between periodontal disease and common malignancies[J]. West China Journal of Stomatology, 2019, 37(3): 320-324.

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