Research progress on the relationship between periodontal disease and common malignancies

doi:10.7518/hxkq.2019.03.018

Abstract

Abstract:

Periodontal disease is a common oral disease that can cause irreversible damage of periodontal support tissue. Studies on the relationship between periodontal disease and malignancies have also increased. In this review, the relationship between periodontal disease and gastrointestinal malignancies (e.g., stomach cancer, colorectal cancer, and pancreatic cancer), lung cancer, and breast cancer are discussed. The related mechanisms are summarized in terms of four aspects, namely, immunity, inflammation, gene, and microbiota and its products, to provide novel methods for the prevention and early diagnosis of malignancies.

Key words: periodontal disease, gastrointestinal malignancies, lung cancer, breast cancer

CLC Number:

R781.4

Yu Hao,Xian Peng,Xuedong Zhou,Lei Cheng. Research progress on the relationship between periodontal disease and common malignancies[J]. West China Journal of Stomatology, 2019, 37(3): 320-324.

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