West China Journal of Stomatology ›› 2012, Vol. 30 ›› Issue (5): 493-497.doi: 10.3969/j.issn.1000-1182.2012.05.010

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Effect to demineralization and remineralization of enamel surface by fluorine

Wu Na1, Zhou Xuedong2, Hao Yuqing2   

  1. 1. Dept. of Conservative Dentistry and Endodontics, The Affiliated Hospital of Stomatology, Chongqing Medical University; Chongqing Research Center for Oral Diseases and Biomedical Science, Chongqing 401147, China; 2. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China
  • Received:2011-11-15 Revised:2012-01-10 Online:2012-10-01 Published:2012-10-01


Objective To analyze the mechanism of fluorine by systemic analysis of fluorination-demineralizationremineralization experiments. Methods The enamel specimens were randomly assigned to untreated group(group A), non-fluoride group(group B), low-fluoride group(group C) and high-fluoride group(group D). The in vitro model of fluoride enamel was established in group C and D. Based on that, the establishment of demineralization model and remineralization experiment by pH-cycling in group B, C and D were followed. All enamel specimens were observed by stereomicroscope and scanning electron microscope and compared in surface microhardness value. Results There was distinct difference in micro-morphologic appearance on fluoride enamel surface. Artificial caries of fluoride enamel showed a relatively complete surface, the surface microhardness after demineralization and remineralization in fluoride group was higher than non-fluoride group(P<0.05). Conclusion The fluorinated enamel can enhance cariostatic potential and remineralization capacity of dental enamel.

Key words: fluorine, enamel, demineralization, remineralization