West China Journal of Stomatology ›› 2024, Vol. 42 ›› Issue (2): 256-261.doi: 10.7518/hxkq.2024.2023240
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Li Guoli(), Lou Jing, Tan Na, Zheng Hong(
)
Received:
2023-09-04
Revised:
2023-12-25
Online:
2024-04-01
Published:
2024-03-26
Contact:
Zheng Hong
E-mail:924761585@qq.com;zhenghonghq@hotmail.com
CLC Number:
Li Guoli, Lou Jing, Tan Na, Zheng Hong. Gingival diffuse large B-cell lymphoma: report of 2 cases[J]. West China Journal of Stomatology, 2024, 42(2): 256-261.
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Tab 1
Clinical findings of gingival DLBCL
参考文献 病例/ | 性别/年龄(岁) | 部位及临床特征 | B症状 | 乳酸脱氢酶 | 影像学 | 肿瘤大小/cm | Ann Arbor分期 | 治疗 | 预后/月 |
---|---|---|---|---|---|---|---|---|---|
1/[ | F/57 | 牙龈溃疡 | / | 正常 | / | 2.5 | ⅠE期 | RT | ANED/79 |
2/[ | F/65 | 牙龈溃疡 | / | 升高 | / | 3.5 | ⅠE期 | R-CHOP+RT | ANED/13 |
3/[ | F/68 | 牙龈溃疡 | / | 正常 | / | 3.5 | ⅠE期 | CHOP+RT | ANED/22 |
4/[ | M/60 | 牙龈溃疡 | / | 正常 | / | 2 | ⅠE期 | R-CHOP+RT | ANED/16 |
5/[ | F/68 | / | / | 升高 | / | >5 | ⅠE期 | / | / |
6/[ | M/62 | 牙龈溃疡 | / | 正常 | / | 2,多个 | ⅠE期 | R-CHOP | ANED/19 |
7/[ | M/76 | 牙龈溃疡 | / | 正常 | / | 4 | ⅠE期 | R-THP-COP+RT | ANED/33 |
8/[ | F/72 | / | / | 正常 | / | 3 | ⅠE期 | / | / |
9/[ | F/62 | 牙龈溃疡 | / | 升高 | / | 1.5 | ⅠE期 | CHOP+RT | ANED/177 |
10/[ | F/77 | 牙龈溃疡 | / | 正常 | / | 3.5 | ⅠE期 | 部分切除+CHOP | ANED/31 |
11/[ | M/57 | / | / | 正常 | / | 3 | ⅡE期 | R-CHOP | ANED/52 |
12/[ | M/73 | 左下颌牙龈肿痛伴溃疡 | / | / | CT显示左下颌到左牙槽区软组织阴影 | 1.5 | ⅠE期 | R-THP-COP | ANED/36 |
13/[ | M/53 | 牙龈肿痛 | / | 正常 | / | / | ⅠE期 | R-CHOP | ANED/18 |
14/[ | M/51 | 牙龈肿痛 | / | 正常 | / | / | / | R-CHOP+RT | 死亡/59 |
15/[ | M/43 | 左下颌牙龈肿痛 | 无 | / | X线片显示弥漫性骨透射线 | 3 | CHOP | ANED/6 | |
16/[ | M/63 | 右上颌牙龈肿痛 | / | / | / | Ⅱ期 | RT | 死亡/29 | |
17/[ | F/69 | 左上颌牙龈肿物 | / | / | / | Ⅲ期 | CHOP+RT | 死亡/6 | |
18/[ | M/61 | 右上颌牙龈肿物伴溃烂 | 无 | / | MRI显示右上牙龈区团块影 | 3 | / | 化疗 | / |
19/[ | M/84 | 右上颌牙龈肿物 | 无 | 正常 | X线显示上颌团块影 | 0.4 | ⅠE期 | 未治疗 | 消退/24 |
20/[ | F/61 | 右上颌牙龈肿痛 | / | 正常 | / | / | / | 未治疗 | 消退/22 |
21/[ | M/67 | 右下颌牙龈肿痛 | 无 | / | CT显示软组织密度影 | / | / | 化疗 | ANED/12 |
病例1 | M/79 | 右下颌牙龈溃疡 | 无 | / | CT提示软组织稍增厚 | 1.5 | / | 未治疗 | 死亡/12 |
病例2 | M/83 | 右上颌牙龈肿物 | 无 | / | / | 5 | / | 未治疗 | 死亡/1 |
Tab 2
Immunohistochemical findings of gingival DLBCL
病例/参考文献 | EBER | CD3 | CD5 | CD10 | CD20 | CD138 | BCL6 | MUM1 | Ki-67/% | 分型 |
---|---|---|---|---|---|---|---|---|---|---|
1/[ | - | - | - | - | + | - | - | + | 85 | ABC |
2/[ | + | - | - | - | + | - | - | + | 75 | ABC |
3/[ | - | - | - | - | + | - | - | + | 60 | ABC |
4/[ | - | - | - | - | + | - | - | + | 90 | ABC |
5/[ | - | - | - | + | + | - | + | - | 80 | GCB |
6/[ | + | - | - | - | + | - | + | + | 70 | ABC |
7/[ | - | - | - | - | + | - | + | + | 80 | ABC |
8/[ | - | - | - | + | + | - | + | + | 50 | GCB |
9/[ | - | - | - | - | + | - | + | + | 65 | ABC |
10/[ | - | - | - | - | + | - | + | + | 80 | ABC |
11/[ | - | - | - | - | + | - | - | + | 90 | ABC |
12/[ | - | - | - | - | + | - | + | + | 90 | ABC |
13/[ | / | / | / | / | + | / | / | / | / | / |
14/[ | / | - | / | - | + | / | + | + | 70 | ABC |
15/[ | / | - | / | - | + | / | + | - | 60 | GCB |
16/[ | - | - | - | + | + | / | + | + | 90 | GCB |
17/[ | - | - | - | + | + | / | + | - | 90 | GCB |
18/[ | / | - | / | - | + | - | - | + | 70 | ABC |
19/[ | - | - | / | / | + | / | / | / | 90 | / |
20/[ | - | - | - | - | + | / | + | - | 90 | GCB |
21/[ | / | - | - | - | + | - | - | + | 60 | ABC |
病例1 | / | - | - | + | + | - | + | + | 90 | GCB |
病例2 | - | - | - | - | + | / | + | + | 90 | ABC |
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