Abstract:

Objective To provide content- measuring evidences for establishing the quality criteria of dexamethasone acetate ulcer pasta. Methods Content of dexamethasone acetate was assayed by the isonicotinyl hydrazine（INH） colorimetry. Results The good linear range was 6 - 16 μg/mL（r=0.999 1）. The average recovery of dexamethasone acetate was 98.9%, and relative standard deviation was low than 1%（n=5）. Conclusion It is easy, convenient, accurate and dependable for INH colorimetry to determine the content of dexamethasone acetate.

Key words: dexamethasone acetate, isonicotinyl hydrazine colorimetry, content assaying, ulcer pasta