Abstract:

Objective　To investigate the feasibility and clinical results of applying poly-DL-lactic acid (PDLLA) biomem- branes in cleft palate repair.Methods　68 cleft palate patients were divided into study group and control group. The traditional surgical method was used to control group to close the soft cleft palate, and the PDLLAbiomembrane was used to study group and implanted into the surgical gap between the periosteum and bone at the hard palate, and fixed with suture. The duration, blood loss at operation, post-operative complication, wound healing and recoverywere recorded and compared to conventional cleft palate repair.Results　Operationswere successfully completed on all 34 patients. Wound healing of soft palate and uvulawas uneventful with no incidence of fistula or dehiscence. The primary healing on tissue defect of hard palate occurred in 29 patients, secondary healing occurred in 3 patients, permanent fistula between the oral cavity and the nasal cavity occurred in only one patients, and 3 patients left over fistula on alveolar process. Compared totraditional cleft palate repair, blood loss and incidence of fistula on alve- olar process were decreased; the average surgical time was 89·25 minutes and was not prolonged; and there was no significant in- crease in post-operative complication.Conclusion　Hard cleft palate repairwith PDLLAbiomembranes is safe, simple and practi- cal with good clinical results and is beneficial to minimize the bad influences towards the development and growth for maxilla of cleft palate patients.

Key words: hard cleft palate repair, absorbable membranes for clinical usage, poly-DL-lactic acid, membrane guided ti- ssue regeneration