Abstract:

Objective　To examine serum IL-2 and IL-6 levels in BMS patientswith orwithout depression and make clear the relationship between serum IL-2, IL-6 and mood disorder.Methods　Serum IL-2 and IL-6 were examined in 48 BMS patients by means of ELISA. The Hamilton Depression Rating Scale (HDRS) was used to evaluate the depressive symptomatology.Results 　There was no significant difference in serum IL-2 and IL-6 among BMS patients with orwithout depression. Mood disorderwas not correlated to serum IL-2 and IL-6, but positively correlated to pain levels.Conclusion　Depression status may not influence serum IL-2 and IL-6 levels significantly, but it has a relationshipwith BMS. TheHDRS can be used to determine depression status in BMS patients in order to help clinical treatment.

Key words: burning mouth syndrome, IL-2, IL-6, mood disorder