West China Journal of Stomatology

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Experimental Research with Animal on Super-high Molecular Weight Poly-DL-lactic Acid Internal Fracture-fixing System Used to Treat Mandible Fracture

Zheng Qian, Liu Lei, Wei Shicheng, et al   

  1. Zheng Qian, Liu Lei, Wei Shicheng, et al West China College ofStomatology, Sichuan University Zhao Zonglin ChiefHospitalofChengdu MilitaryArea Xiong Chengdong, Luo Fucheng Chengdu Institute ofOrganic Chemistry, Chinese AcademyofSciences
  • Received:2002-08-25 Revised:2002-08-25 Online:2002-08-20 Published:2002-08-20

Abstract:

Objective:The purpose of this study was to evaluate the safety and therapy effects of super-high molecular weight poly-DL- lactic acid (PDLLA) internal fracture-fixing system on the treatment of mandible fracture in dogs.Methods:The authors treated dogscmandible fracture with super-high molecularweight polylactic acid internal fracture-fixing system and observed the activity of these dogs. In 1, 3, 6, 12 months after the operation, the authors took the specimens out from dogs and evaluated with anatomi- cal, pathological and radiographic methods.Results:The therapeutic effects of super-high molecularweight PDLLA internal frac- ture-fixing system are similarwith that of stainless steel internal fracture-fixing systems.Conclusion:Super-high molecular weight PDLLA internal fracture-fixing system can be used in the treatment of mandible fracture.

Key words: poly_DL_lacticacid, mandible fracture, internal fracture_fixing systemdogs, dogs