Expression of myofibroblast in gingival after orthodontic loading

doi:10.7518/hxkq.2019.05.016

Abstract

Abstract:

Objective To examine the expression of myofibroblast in gingival after orthodontic loading. Methods Eight patients were selected as experimental group and treated with orthodontic force for 4 months. Ten patients were selected as the control group, were not loaded. The gingival protein expressions of collagen typeⅠ, collagen type Ⅲ, α-smooth muscle actin (α-SMA) were evaluated by immunohistochemistry method. Results Positive expressions of collagen typeⅠ, collagen type Ⅲ were founded, while no positive staining for α-SMA in the gingival tissue except vascular epithelium before loading. In experimental group, collagen type I and collagen type Ⅲ were increased after orthodontic loading (P<0.05), the expression of α-SMA was detected and statistically significant (P<0.05). Conclusion The myofibroblast exists in gingival tissue after orthodontic loading, and it may be concerned with orthodontic teeth relapse.

Key words: orthodontics, gingival, myofibroblast, α-smooth muscle actin

CLC Number:

R783.5

Meng Yao,Liu Man,Deng Qiannan. Expression of myofibroblast in gingival after orthodontic loading[J]. West China Journal of Stomatology, 2019, 37(5): 537-540.

Figures/Tables 2

References 13

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测量项目	MOD值			t值	P值
测量项目	加力前（n=10）	加力后（n=8）	前后差值	t值	P值
Col Ⅰ	0.156 3±0.039 1	0.168 7±0.041 3	-0.012 3±0.005 6	-5.883	0.028*
Col Ⅲ	0.165 4±0.028 1	0.190 3±0.029 9	-0.024 9±0.008 3	-22.904	0.002*
α-SMA	0.129 3±0.093 9	0.202 5±0.074 1	-0.073 2±0.020 8	-6.087	0.026*

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