West China Journal of Stomatology ›› 2021, Vol. 39 ›› Issue (6): 724-727.doi: 10.7518/hxkq.2021.06.016

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Experience in the diagnosis and treatment of a drug-induced pemphigus

Yuan Peiyang1(), Qiu Min1,2, Wan Zixin3, Jiang Lu1()   

  1. 1.State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
    2.Dept. of Oral Medicine, Stomatology Center, Shenzhen People, s Hospital, Shenzhen 518020, China
    3.State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Oral Pathology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2020-09-11 Revised:2021-05-18 Online:2021-12-01 Published:2021-12-03
  • Contact: Jiang Lu E-mail:yuanpeiyangvip@163.com;jianglu@scu.edu.cn
  • Supported by:
    The National Natural Science Foundation of China(81670998)

Abstract:

Drug-induced pemphigus (DIP) is a special type of pemphigus, and its pathogenesis, characteristics of treatment, and prognosis are closely related to the inducing drugs. This article reports the diagnosis and treatment of DIP (pemphigus vulgaris) caused by the administration of rifampin to a patient with tuberculosis. Combined with the literature, we discussed the types, pathogenesis, differential diagnosis, and treatment principles of DIP. We propose that in the oral clinical practice for patients with pemphigus vulgaris, the importance of investigating suspected drugs that induce DIP should be emphasized.

Key words: drug-induced pemphigus, rifampin, pemphigus vulgaris, tuberculosis

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