Localized juvenile spongiotic gingival hyperplasia: a case report

doi:10.7518/hxkq.2024.2024023

Abstract

Abstract:

Localized juvenile spongiotic gingival hyperplasia (LJSGH) is a kind of gingival hyperplasia with unique pathological manifestations. Its clinical manifestations are atypical, and the etiology and pathogenesis are unclear. No case report was reported in China. The diagnosis of this disease mainly relies on pathological testing, and recurrence may occur after treatment. The best treatment method still lacks medical evidence. This paper reports a case of LJSGH in a teenager and summarizes its clinical, pathological, and treatment through literature review. This work provides a reference for the diagnosis and treatment of this disease.

Key words: localized juvenile spongiotic gingival hyperplasia, gingiva, periodontal surgery

CLC Number:

R781.4

Yang Jingmei, Zeng Xin, Wu Yafei, Zhao Huan. Localized juvenile spongiotic gingival hyperplasia: a case report[J]. West China Journal of Stomatology, 2024, 42(5): 667-670.

Figures/Tables 4

References 16

1	Darling MR, Daley TD, Wilson A, et al. Juvenile spongiotic gingivitis[J]. J Periodontol, 2007, 78(7): 1235-1240.
2	Argyris PP, Nelson AC, Papanakou S, et al. Localized juvenile spongiotic gingival hyperplasia featuring unusual p16INK4A labeling and negative human papillomavirus status by polymerase chain reaction[J]. J Oral Pathol Med, 2015, 44(1): 37-44.
3	Chang JYF, Kessler HP, Wright JM. Localized juvenile spongiotic gingival hyperplasia[J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2008, 106(3): 411-418.
4	Decani S, Lodi G, Sardella A, et al. Localised juvenile spongiotic gingival hyperplasia: a case of spontaneous resolution and a literature review[J]. Eur J Paediatr Dent, 2021, 22(2): 159-162.
5	Theofilou VI, Pettas E, Georgaki M, et al. Localized juvenile spongiotic gingival hyperplasia: microscopic va-riations and proposed change to nomenclature[J]. Oral Surg Oral Med Oral Pathol Oral Radiol, 2021, 131(3): 329-338.
6	MacKenzie IC, Gao Z. Patterns of cytokeratin expression in the epithelia of inflamed human gingiva and pe-riodontal pockets[J]. J Periodontal Res, 1993, 28(1): 49-59.
7	孟焕新. 牙周病学[M]. 5版. 北京: 人民卫生出版社, 2020: 133-144.
	Meng HX. Periodontology[M]. 5th ed. Beijing: People’s Medical Publishing House, 2020: 133-144.
8	梁静, 高一珂, 张琦玥, 等. 青少年局限性海绵状牙龈增生的诊疗进展[J]. 临床口腔医学杂志, 2022, 38(3): 179-182.
	Liang J, Gao YK, Zhang QY, et al. Progress in diagnosis and treatment of localized spongiform gingival hyperplasia in adolescents[J]. J Clin Stomatol, 2022, 38(3): 179-182.
9	Allon I, Lammert KM, Iwase R, et al. Localized juvenile spongiotic gingival hyperplasia possibly originates from the junctional gingival epithelium: an immunohistoche-mical study[J]. Histopathology, 2016, 68(4): 549-555.
10	Kalogirou EM, Chatzidimitriou K, Tosios KI, et al. Localized juvenile spongiotic gingival hyperplasia: report of two cases[J]. J Clin Pediatr Dent, 2017, 41(3): 228-231.
11	Shimono M, Ishikawa T, Enokiya Y, et al. Biological characteristics of the junctional epithelium[J]. J Electron Microsc (Tokyo), 2003, 52(6): 627-639.
12	Lafuente-Ibáñez de Mendoza I, Alberdi-Navarro J, Mari-chalar-Mendia X, et al. Characterization of juvenile spon-giotic gingival hyperplasia as an entity of odontogenic origin[J]. J Periodontol, 2019, 90(12): 1490-1495.
13	Silveira HA, Toral-Rizo VH, Lara-Carrillo E, et al. Spon-giotic hyperplasia of the oral mucosa: case series and immunohistochemical analysis[J]. Oral Maxillofac Surg, 2022, 26(2): 333-337.
14	de Freitas Silva BS, Silva Sant’Ana SS, Watanabe S, et al. Multifocal red bands of the marginal gingiva[J]. Oral Surg Oral Med Oral Pathol Oral Radiol, 2015, 119(1): 3-7.
15	Nogueira VKC, Fernandes D, Navarro CM, et al. Cryotherapy for localized juvenile spongiotic gingival hyperplasia: preliminary findings on two cases[J]. Int J Paed Dentistry, 2017, 27(3): 231-235.
16	Vieira DL, Leite AF, de Souza Figueiredo PT, et al. A conservative approach for localized spongiotic gingivitis hyperplasia using photodynamic therapy: a case report and review of the literature[J]. Photobiomodul Photomed Laser Surg, 2019, 37(1): 57-61.

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