Research progress in the osteogenetic mechanism of strontium

doi:10.7518/hxkq.2020.06.016

Abstract

Abstract:

Strontium (Sr) is an essential trace element and widely exists in nature. It plays an important role in the in vivo regulation of bone metabolism. Sr locates below Fe in the periodic table, and its chemical structure and polarity are similar to those of Ca. It can induce bone mesenchymal stem cells to differentiate into osteoblasts by inhibiting the activity of osteoclasts and reducing bone resorption. It promotes bone formation through a series of related pathways. The mechanism of Sr regulation of bone metabolism has been extensively researched in recent years. The current study aims to investigate the mechanism of Sr and provide a theoretical basis for its clinical application.

Key words: strontium, bone metabolism, mechanism of action

CLC Number:

Q593⁺.6

Zhong Ningying, Wang Liping. Research progress in the osteogenetic mechanism of strontium[J]. West China Journal of Stomatology, 2020, 38(6): 697-703.

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