West China Journal of Stomatology ›› 2019, Vol. 37 ›› Issue (2): 224-228.doi: 10.7518/hxkq.2019.02.017

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Bisphosphonate-related osteonecrosis of the jaw complicated with wrist scaphoid osteomyelitis: a case report

Zhaowei Sun1,Zhiyong Li1(),Dan Yu2,Jieying Zhu1,Yidian Zhang2,Xinmei Zhu1   

  1. 1.Dept. of Oral and Maxillofacial Surgery, Stomatology Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China
    2.Dept. of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China
  • Received:2018-06-10 Revised:2018-11-08 Online:2019-04-01 Published:2019-04-28
  • Contact: Zhiyong Li E-mail:hxlzy2002@zju.edu.cn

Abstract:

Bisphosphonates can directly inhibit osteoclasts, which may lead to increased bone density, reduced blood flow, and osteonecrosis of the jaw. Bisphosphonate-related osteonecrosis is usually observed in the jaw bone. In this article, we report a patient with bisphosphonate-related osteonecrosis of the jaw (BRONJ) complicated with wrist scaphoid osteo-myelitis. Furthermore, we introduce the pathogenesis, treatment, and prevention of BRONJ.

Key words: bisphosphonate, osteonecrosis of the jaw, scaphoid osteomyelitis, zoledronic acid

CLC Number: