West China Journal of Stomatology

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Effect of Para-aminobenzonic Acid(PABA) on Cell-Surface Hydrophobicity ofStreptococcus Mutans

LI Yan-hong1, ZHOUXue-dong2,XIAOXiao-rong2,LIJi-yao2,LIUQian2,LI Gang2   

  1. 1.Dept.ofPreventive Dentistry,the First Affiliated Hospital ofKunmingMedical University,Kunming650031,China;2.Dept.ofOral Medicine,West China College ofStomatolo- gy,Sichuan University,Chengdu610041,China
  • Received:2004-04-25 Revised:2004-04-25 Online:2004-04-20 Published:2004-04-20

Abstract:

Objective To study the effect of Para-aminobenzonic acid on cell-surface hydrophobicity ofStreptococcus mutans. Methods Microbial adhesion to hydrocarbons (MATH) was used to measure the cell-surface hydrophobicity ofStreptococcus mu- tanswhich grew in modified Carlsson mediumwith different dilutions of PABA.Results The cell-surface hydrophobicity ofStrep- tococcus mutansincreased when Carlsson medium contained low dilution of PABA. But following the increase of PABA, the cell- surface hydrophobicity decreased.Conclusion Para-aminobenzonic acid could inhibit the adherence ofStreptococcus mutans through changing its cell-surface hydrophobicity.

Key words: Streptococcus mutans, hydrophobicity, para-aminobenzoic