Abstract:

Objective To explore the incidence, influence factors and treatment methods of oral mucositis（OM）following hematopoietic stem cells transplantation（HSCT）. Methods A clinical analysis about the total 71 OM cases occurring after HSCT among 166 patients in Peking University People’s Hospital during 2009 was completed. Results The healing rate of OM was 95.77% and the average healing time was（17.61±8.36）d after HSCT. There were no obvious effects of gender, age, HLA matches, conditioning regimen to the healing time of OM（P>0.05）. Conclusion Gender, age, HLA matches and conditioning regimen have no obvious effects on healing time. By given timely and effective treatment, the incidence of OM can be reduced and even severe OM can also be well cured.

Key words: hematopoietic stem cell transplantation, oral mucositis, influence factors, treatment measure