West China Journal of Stomatology

Previous Articles     Next Articles

Ultrastructure of Poly-DL-lactic Acid as GTR Membrane of Soft Tissue Defects in Goats Palates

LUO En1, HU Jing1, NING Qiu1, YU Lan2, ZHOU Yong3, WEI Shi-cheng4   

  1. 1. Dept. of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, Chengdu 610041, China；2. Dept. of Stomatology, Anzhen Hospital, Capital Medical University, Beijing 100029, China； 3. Majing Hospital of Shifang City, Shifang 618400, China； 4. Dept. of Oral and Maxillofacial Surgery, School of Stomatology, Peking University, Beijing 100081, China
  • Received:2006-02-25 Revised:2006-02-25 Online:2006-02-20 Published:2006-02-20

RichHTML

1

PDF (PC)

462

Cited

1

Abstract:

Objective  To study the ultrastructure changes of PDLLA as GTR membrane of soft tissue defects in the palates of goats. Methods  To establish penetrating rectangle palate defects in 8 goats. PDLLA membranes were implanted into the defect areas to guide the regeneration of the soft tissue defects. In 1, 2, 4, 6 months after the operation, the membranes were observed with scanning electron microscope. Results  The surface of PDLLA membrane was regular network before implantation. 1 month after the implantation, the edge of network became blunt. 2 months after the implantation, the surface of PDLLA membrane became coarse and irregular. 4 months after the implantation, PDLLA membrane network collapsed. 6 months after the implantation, PDLLA degraded into scraggly accumulation. Conclusion  PDLLA membrane supplies good supporting function during concrescence of the soft tissue defects. PDLLA gradually loses mechanic intensity and is absorbed.

Key words: poly-DL-lacticacid, GTRmembrane, degradation, ultrastructure

Powered by Beijing Magtech Co. Ltd
This work is licensed under a Creative Commons Attribution 3.0 License.