West China Journal of Stomatology

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Influence of thermochemother apy on the activity of cytotoxic T lymphocyte in or al maxillofacial cancer patients

GUO Jun1, MEN Chang- jie2, WANG Sheng- zhi3, GAO Xiang- dong3, CHENG Zhou3, MAO Zu- yi4, WANG Dazhang4   

  1. 1. Dept. of Surgery, The Branch Hospital of Yantai Yuhuangding Hospital, Yantai 264003, China；2. Dept. of Stomatology, The Penglai People′s Hospital, Penglai 265600, China；3. Dept. of Oral and Maxillofacial Surgery, Yantai Yuhuangding Hospital, Yantai 264000, China； 4. Dept. of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2007-10-25 Revised:2007-10-25 Online:2007-10-20 Published:2007-10-20
  • Contact: WANG Sheng- zhi，Tel：0535- 6691999

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Abstract:

Objective To study the influence of thermochemotherapy on the activity of cytotoxic T lymphocyte （CTL） in peripheral blood of patients with oral maxillofacial cancer. Methods Twenty - one subjects with oral maxillofacial cancer were treated by thermochemotherapy, and the activity of CTL in peripheral blood was analyzed. Results Thermochemotherapy can obviously enhance the activity of CTL（P<0.01）. Conclusion Thermochemotherapy can enhance the activity of CTL, thus enhance the patient′s immune function. Therefore, it can enhance the antitumor response in whole body.

Key words: thermochemotherapy, cytotoxic T lymphocyte, oral tumor

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