West China Journal of Stomatology

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Typing Human Papillonta Virus( HPV) Infection in the Warts of Oral Mucasa from HIV-positive Patients

MA San- cheng1,HU Jing1,ZHAO Jin2,PAU1 Speight3   

  1. 1.Dept.of Oral and Maxillofacial Surgery, West China College of Stomatolo- gy, Sichuan University, Chengdu 610041,China; 2. Dept .of Oral Medicine,West China College of Stomatology, Sichuan Uni- 。勿.Chengdu 610041,China; 3. Eastnwn Dental Institute,University College of London,London WCIX 8LD, UK
  • Received:2004-10-25 Revised:2004-10-25 Online:2004-10-20 Published:2004-10-20

Abstract:

Objective To detect and type human papilloma virus (HPV) in the warts of oral mucosa from HIV-positive patients, and better understand the biological characters of these oral warts. Methods Polymerase chain reaction MR)~used to detect and type HPV infection by concensus HPV primers Gp5+/Gp6+ and specific HPV primers ( HPV6/II,16, 18, 31, 33) in 34 cases of oral mucosa warts from HIV-positive patients. Results The HPV infection rate was 88.2% by consensus HPV primers Gp5十/Gp6十;the HPV infection rate of HPV6/II,16, 18, 31 was respectively 47.06%,11.67 %;2.94%,and 5.88% by specific HPV primers. Conclusion Most lesions of oral warts from HIV-positive patients are associated with the infection of HPV. The low risk HPV6/11 infection is more common than the high risk HPV16, 18, 31.

Key words: warts, humanpapillomavirus, polymerasechainreaction