West China Journal of Stomatology ›› 2016, Vol. 34 ›› Issue (6): 643-646.doi: 10.7518/hxkq.2016.06.018

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Development of transcriptional regulators of Streptococcus mutans in cariogenic virulence

Li Lan1, Zhang Bowen2, LiJiyao1   

  1. 1. State Key Laboratory of Oral Diseases, Dept. of Conservative Dentistry and Endodontics, West China Hospitalof Stomatology, Sichuan University, Chengdu 610041, China; 2. State Key Laboratory of Oral Diseases, Dept. of Head andNech Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China)Supported by: The National Natural Science Foundation of China (81371135). Correspondence: Li Jiyao, E-mail: jiyao_li@aliyun.com.
  • Received:2015-10-12 Revised:2016-09-10 Online:2016-12-01 Published:2016-12-01

Abstract: Some transcriptional regulators contribute to the expression of Streptococcus mutans (S. mutans) cariogenicvirulence factors. Although the target sequence transcriptional regulators anchored on the cell wall and the molecular mechanismof the regulation of S. mutans are yet to be clarified, certain global regulators potentially associated with the cariogenicityof S. mutans have been identified. This review is about these related transcriptional regulators, their function, and possiblemechanisms.

Key words: Streptococcus mutans, cariogenic virulence, transcriptional regulator

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