Treatment of multiple adjacent gingival recessions with an acellular dermal matrix or a connective tissue graft: a Meta-analysis

doi:10.7518/hxkq.2022.06.010

Abstract

Abstract:

Objective To evaluate the effectiveness of an acellular dermal matrix or a connective tissue autograft in the treatment of multiple adjacent gingival recessions through Meta-analysis. Methods Randomized controlled trials were screened in four electronic databases in English according to the inclusion and exclusion criteria until April 20, 2022. The main outcome indicators were keratinized gingival tissue width, recession depth, probing depth, clinical attachment level, complete root coverage, and root coverage esthetic score. Results Seven randomized controlled trials were included. After 12 months, the connective tissue graft in the control group could increase the keratinized gingival tissue width [mean difference (MD)=-0.28 (-0.47, -0.08), P=0.006], reduce the gingival recession depth [MD=0.23 (0.12, 0.35), P<0.000 1], and improve the complete root coverage [risk ratio=0.80, 95% confidence interval (0.69, 0.93), P=0.003] compared with the acellular dermal matrix in the experimental group. No significant difference was found in probing depth, clinical attachment level, and root coverage esthetic score between groups. Conclusion Connective tissue grafts have advantages in increasing the keratinized gingival tissue width, reducing the gingival recession depth, and improving the complete root coverage in surgeries for treating multiple adjacent gingival recessions. Acellular dermal matrices also have some clinical value in terms of operation simplicity and similar effectiveness.

Key words: multiple adjacent gingival recessions, connective tissue graft, acellular dermal matrix, Meta-analysis

CLC Number:

R 781.4

Cong Zhaoxia, Liu Yuan, Zhao Jin. Treatment of multiple adjacent gingival recessions with an acellular dermal matrix or a connective tissue graft: a Meta-analysis[J]. West China Journal of Stomatology, 2022, 40(6): 690-697.

Figures/Tables 9

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纳入研究	研究设计	总人数/总牙数	年龄/岁	联合术式	ADM		CTG		随访时间/月	结局指标
纳入研究	研究设计	总人数/总牙数	年龄/岁	联合术式	牙数	退出人数	牙数	退出人数	随访时间/月	结局指标
Koudale 2012^[12]	平行对照	10/20	22.5±8.23	CAF	10	0	10	0	6	KTW、RD、PD、CAL、CRC
Thakare 2015^[13]	平行对照	20/44	29.7±4.35	CAF	21	0	23	0	6	KTW、RD、PD、CAL、CRC
Rakasevic 2020^[14]	半口对照	20/114	30.5±7.9	MCAT	62	0	52	0	12	KTW、RD、PD、CAL、CRC、RES
Gürlek 2020^[15]	半口对照	15/>82	31.41±13.32	MCAF	41	3	41	3	18	KTW、RD、PD、CAL、CRC
Meza-Mauricio 2021^[16]	平行对照	42/132	37.2	CAF	66	2	66	0	12	KTW、RD、PD、CAL、CRC、RES
Maluta 2021^[17]	半口对照	15/94	37.47±9.01	CAF	48	0	46	0	6	KTW、RD、PD、CAL、CRC
Vincent-Bugnas 2021^[18]	半口对照	12/74	41.2±10.9	MCAT	37	0	37	0	12	KTW、RD、PD、CAL、CRC

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