Abstract:

Objective This study aims to evaluate the quality of life (QOL) of patients who underwent resection of oral cancer and reconstruction by free anterolateral thigh perforator flaps (ALTF). Methods A total of 32 patients with oral and maxillofacial malignancies who had undergone the resection of oral cancer and reconstruction by ALTF were retrospectively analyzed. At 12 months postoperatively, the QOL of these patients was assessed by using the 14-item oral health impact profile (OHIP-14) and the medical outcome study short form-36 (SF-36) questionnaires. Results A total of 32 questionnaires were collected. In SF-36, the highest scoring domains were bodily pain (78.58±14.82), physical functioning (72.08±27.86), and the role of physical (60.00±42.63), whereas the lowest scoring domains were role-emotional (41.67±39.62), followed by mental health (50.75±13.07) and health transition (54.17±21.75). In OHIP-14, the lowest scoring domains were social disability (34.50±11.32) and handicap (36.04±12.05), indicating the functional recovery was better; and the highest scoring domains were physical pain (73.50±18.96) and psychological discomfort (60.17±20.66), indicating the functional recovery was worse. Conclusion The ALTF is an ideal selection for the reconstruction of oral defects after cancer resection. In using this flap, the basic social need of patients after surgery can be satisfied. Moreover, the appearance and the functions of chewing, deglutition, and speech can be restored in varying degrees. Thus, ALTF can improve the patients’ QOL.

Key words: quality of life, oral cancer, surgical flaps, reparative and reconstructive surgery