West China Journal of Stomatology

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Adhesion to Buccal Epithelial Cells ofCandida albicansIsolates from Oral Lichen Planus

ZENG Xin1,CHEN Qian-ming1,NIEMin-hai2,LIBing-qi1   

  1. 1.Dept.ofOral Medicine,West China College ofStomatology,Sichuan University,Cheng- du610041,China;2.Dept.ofOral Medicine,School ofStomatology,Luzhou Medical College,Luzhou646000,Chin
  • Received:2005-12-25 Revised:2005-12-25 Online:2005-12-20 Published:2005-12-20

Abstract: Objective To investigate the adhesion to buccal epithelial cells ofCandida albicansisolates from erosive oral li- chen planus(OLP) and nonerosive OLP, and its role in the development of OLP.Methods A total of 112 isolates, comprising healthy control (26),erosive OLP (62) and nonerosive OLP (24), were screened for the adhesion by using buccal epithelial cell (BEC) assay.Results The adhesion to buccal epithelial cells of the isolates from erosive OLP group was stronger than that of those from healthy control.Conclusion Candida albicans, some isolates with a special virulence attribute may contribute to the occurrence and progression of erosive OLP.

Key words: Candida albicans, adhesion to buccal epithelial cells, oral lichen planus