Clinical and imaging features of eight cases of Ewing sarcoma of the jaw

doi:10.7518/hxkq.2023.2022325

Abstract

Abstract:

Objective This study investigate the clinical and imaging features of Ewing sarcoma (ES) of the jaw. Methods Eight cases of pathologically diagnosed ES of the jaw from January 2010 to June 2022 were included in the study. Clinical and radiological features were retrospectively analyzed. Results Among the eight cases, the mean age at onset was 29.4 years, and the male to female ratio was 7∶1. The predilecting site was the posterior part of mandible, accounting for 75% of the cases. The lesions often exhibited early numbness of the lower lip and lymphadenopathy. The main radiographic manifestation of mandibular lesions was ill-defined radiolucency, mixed with fibrous or brush-like tumor matrix, and soft tissue mass. The maxillary ES lesions mainly presented as lytic bone destruction accompanied by adjacent soft tissue mass. Periosteal ossification was rarely seen. Conclusion The clinical and imaging characteristics of ES in the jaw are helpful for its diagnosis.

Key words: jaw, Ewing sarcoma, imaging features, clinical manifestation

CLC Number:

R 739.82

Feng Yinglian, Wang Tiemei, Lin Zitong, Zhang Lei, Huang Xiaofeng, Sun Guowen, Xia Shu. Clinical and imaging features of eight cases of Ewing sarcoma of the jaw[J]. West China Journal of Stomatology, 2023, 41(2): 185-189.

Figures/Tables 4

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病例序号	年龄/岁	性别	病程	有无肿块	面部形态	神经症状	发病部位
1	9	男	2月余	有	稍不对称	右下唇麻木	右下颌骨后部
2	16	男	2月余	有	尚对称	无	右下颌骨后部
3	29	男	2月余	有	基本对称	左下唇麻木	左下颌骨后部
4	55	男	4月余	有	不对称	右下唇麻木	右下颌骨后部
5	21	男	6月余	有	不对称	右下唇麻木	右下颌骨后部
6	16	男	2月余	有	不对称	左下唇麻木	左下颌骨后部
7	62	男	3月余	有	不对称	无	右上颌骨后部
8	27	女	5月余	有	稍不对称	无	右上颌骨后部

病例	影像特点	大小/cm	颌骨膨隆	软组织肿块形成	边界	骨皮质不完整	病灶密度	周围组织受累	骨膜成骨	与神经管分界	淋巴结肿大	初步影像学诊断
1	膨胀性	5.8×3.6	颊舌侧	有	溶蚀状及	有	不均匀，可见纤维	有	无	不清晰	双侧颌下淋巴结	巨细胞病变可
	骨质破坏		膨隆		虫蚀状		状及放射状瘤骨				（Ⅰ区）肿大	能，骨肉瘤待排
2	混杂低密度	3.6×2.9	颊侧	有	溶蚀状	有	不均匀，可见絮	有	无	\	双侧颈深上淋巴结	原始神经外胚层
	骨破坏		稍膨隆				状、毛刷状瘤骨				（Ⅱ区）肿大	肿瘤可能
3	混杂低密度	4.5×1.9	颊舌侧	有	虫蚀状	有	不均匀，可见毛刷	有	无	不清晰	左侧颈深上淋巴结	ES？骨肉瘤？
	骨破坏		稍膨隆				状瘤骨				（Ⅱ区）肿大
4	混杂低密度	6.2×4.0	颊舌侧	有	溶蚀状及	有	不均匀，可见纤维	有	无	不清晰	无	侵袭性病变可
	骨破坏		膨隆		虫蚀状		状瘤骨					能，骨肉瘤？
5	广泛	7.0×5.2	颊舌侧	有	虫蚀状	有	欠均匀，可见毛刷	有	无	不清晰	右侧颌下淋巴结	侵袭性病变
	骨质破坏		膨隆				状、斑片状瘤骨				（Ⅰ区）肿大
6	混杂低密度	5.5×4.5	颊舌侧	有	虫蚀状	有	不均匀，可见纤维	有	无	不清晰	左侧颌下淋巴结	骨肉瘤可能
	骨破坏		膨隆				状瘤骨				（Ⅰ区）肿大
7	骨质破坏伴	5.1×3.9	颊侧	有	溶蚀状	有	不均匀	有	无	\	无	侵袭性病变
	软组织肿块		膨隆
8	骨质破坏伴	5.9×4.4	无	有	溶蚀状	有	尚均匀	有	无	\	无	侵袭性病变
	软组织肿块

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