West China Journal of Stomatology ›› 2020, Vol. 38 ›› Issue (6): 681-686.doi: 10.7518/hxkq.2020.06.013

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Gene polymorphism in oral lichen planus

Pan Yingxiao(), Guo Dawei, Li Xin, Liu Hengyi, Lu Shulai()   

  1. Dept. of Stomatology, Qingdao University & Dept. of Stomatology, Affiliated Qingdao Municipal Hospital, Qingdao University, Qigndao 266000, China
  • Received:2019-04-07 Revised:2020-06-29 Online:2020-12-01 Published:2020-12-07
  • Contact: Lu Shulai E-mail:panyingxiao01@163.com;lshl97@163.com
  • Supported by:
    Qingdao Science and Technology Project(17-3-3-39-nsh);General Program of Medical Health Science and Technology Development Project of Shandong Province(2015WS0327);Science and Technology Development Project of Traditional Chinese Medicine of Shandong Provincial Health Commission(2015-378)

Abstract:

Oral lichen planus (OLP) is a common chronic inflammatory disease of the oral mucosa. The prevalence rate of OLP in adults is 0.5%-2%. The etiology and pathogenesis of OLP are still unclear. The pathogenesis of OLP may be related to the genetic polymorphism of some genes. Currently, the gene families, including tumor necrosis factor, interferon, interleukin, enzyme, and receptor, have been extensively studied. This work reviews related studies on gene polymorphism of OLP.

Key words: oral lichen planus, gene polymorphism, genetics, etiology

CLC Number: