West China Journal of Stomatology ›› 2020, Vol. 38 ›› Issue (6): 657-661.doi: 10.7518/hxkq.2020.06.009

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Effect of CO2 fractional laser on the early control of scar post-secondary repair in patients with a cleft lip

Li Yuanyuan(), Wu Min, Liu Mingxi, Xie Chenyang, Zheng Qian, Shi Bing, Li Chenghao()   

  1. State Key Laboratory of Oral Disease & National Clinical Research Center for Oral Diseases & Dept. of Cleft Lip and Palate Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2019-11-18 Revised:2020-08-11 Online:2020-12-01 Published:2020-12-07
  • Contact: Li Chenghao E-mail:372537574@qq.com;leechenghao_cn@163.com
  • Supported by:
    Clinical Research Project of West China Hospital of Stomatology of Sichuan University(LCYJ2019-10)

Abstract:

Objective To observe and compare the clinical efficacy of CO2 fractional laser in the early control of scar post-secondary repair in patients with a cleft lip. Methods In the treatment group, 43 patients with secondary repair of cleft lip were treated via CO2 fractional laser. The control group covered 70 patients post-cheiloplasty. The effect in the two groups after six months was compared. The duration from the beginning of the laser treatment to surgery and patient gender were analyzed to determine if they affected the efficacy of the laser treatment for scars. Results 1) The curative effect in the treatment group was better than that in the control group (P<0.000 1), the total effectiveness rate was 90.7% in the treatment group. 2) No significant statistical difference in efficacy was observed between men and women (P=0.487). Moreover, no significant statistical difference in efficacy (P=0.055) was observed among patients one year after surgery, within the duration of <3 months, and within the duration of ≥3 months. Conclusion CO2 fractional laser had a definite effect on the treatment of scar post-secondary repair in patients with a cleft lip. No significant correlation was observed between treatment effect and patient gender, and no difference was noted among patients one year after surgery. In the beginning of the laser treatment, no difference was observed between the durations of <3 months and ≥3 months after the reconstruction, Therefore, early intervention of scars a year after secondary repair of a cleft lip can achieve good results.

Key words: CO2 fractional laser, secondary repair of the cleft lip, scars

CLC Number: