West China Journal of Stomatology ›› 2018, Vol. 36 ›› Issue (1): 99-103.doi: 10.7518/hxkq.2018.01.019

• Orginal Article • Previous Articles     Next Articles

Effect of inflammaging on periodontitis

Qi Wang1(), Xinyi Zhou1, Yi Ding2()   

  1. 1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China;
    2. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China;
  • Received:2017-04-16 Revised:2017-08-09 Online:2018-02-07 Published:2018-02-01
  • Supported by:
    Supported by: The National Natural Science Foundation of China (81200794, 81371149);National Key Clinical Specialist Construction Programs of China (Periodontics, 2010);International Scientific Cooperation and Exchanges Project of Sichuan Province (2017HH0078).

Abstract:

Inflammaging is the chronic, systematic, and controllable upregulation of a pro-inflammation state with advan-cing age. Chronic low-grade inflammation accompanied by sustained stimuli is correlated with various age-related diseases (ARDs). Recent studies on ARDs have prompted further research interest in the inner mechanisms underlying inflammaging to establish prevention and treatment plans for inflammatory diseases. In this article, we discuss inflammaging and its signi-ficant role in periodontitis.

Key words: periodontitis, inflammaging, inflammasome, age-related diseases

CLC Number: