Research progression of the relationship between integrin α2β1 and drug-induced gingival overgrowth

doi:10.7518/hxkq.2017.01.016

Abstract

Abstract:

Drug-induced gingival overgrowth (DIGO) is characterized by fibrous gingival hyperplasia and increased gin-gival volume. DIGO is histologically associated with proliferation of cells and deposition of extracellular matrices, particularly collagen. Integrin α2β1 is related to collagen phagocytosis and involved in the occurrence and progression of DIGO. This paper reviews the progress of research on the relationship between integrin α2β1 and DIGO.

Key words: drug-induced gingival overgrowth, integrin α2β1, collagens metabolism, collagen phagocytosis

CLC Number:

R781.4

Yingzhu Kang, Shujuan Guo, Chengcheng Liu, Yi. Ding. Research progression of the relationship between integrin α2β1 and drug-induced gingival overgrowth[J]. West China Journal of Stomatology, 2017, 35(1): 99-103.

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