Abstract:

Objective  To determinetheprevalenceofsaliva Helicobacter pylori inLanzhou andinvestigate Helicobacter pylori-related diseases. Methods  Helicobacter pylori was detected through bacterial culture, Gram stain microscopy, and urease test from saliva samples collected from 941 residents of Lanzhou. The infection rate and growth of Helicobacter pylori among the residents were analyzed in terms of different oral health conditions, oral disease, gender, urban and rural status, and age. Results The rate of Helicobacter pylori-positive saliva in Lanzhou was 42.72%. The status of Helicobacter pylori infection showed significant difference among subjects with different oral hygiene and oral diseases. The rate of Helicobacter pylori-positive saliva among females was 47.89%, which was greater compared with the rate among males (38.45%, P=0.004, χ2=8.492). The rate of Helicobacter pylori-positive saliva in the town was 33.99%, which was less than the rate for the villages (50.93%, P=0.000, χ2=27.551). The rate of Helicobacter pylori-positive saliva among residents aged 10 to 59 showed a flat trend with no significant differences. However, the rate of Helicobacter pylori-positive saliva among residents over 60 years old showed a significantincrease. Nosignificant difference was foundinthegrowth of saliva Helicobacter pylori (P=0.086). Conclusion The rate of Helicobacter pylori-positive saliva isrelated to thesubjects’ oralhygiene, oral disease, gender, age, and living conditions. 

Key words: Helicobacter pylori,  , bacterial culture,  , Lanzhou