华西口腔医学杂志 ›› 2022, Vol. 40 ›› Issue (1): 106-110.doi: 10.7518/hxkq.2022.01.016

• 病例报告 • 上一篇    下一篇

Warthin样黏液表皮样癌、Warthin瘤合并黏液表皮样癌及伴黏液化生3

赵好为(), 韩琪, 孙小钦, 王韵, 陈宇()   

  1. 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心 四川大学华西口腔医院病理科,成都 610041
  • 收稿日期:2020-11-17 修回日期:2021-03-19 出版日期:2022-02-01 发布日期:2022-02-07
  • 通讯作者: 陈宇 E-mail:ZhaoHaowei95@hotmail.com;chen_yu55@hotmail.com
  • 作者简介:赵好为,硕士,E-mail:ZhaoHaowei95@hotmail.com

Warthin-like mucoepidermoid carcinoma and mucoepidermoid carcinoma, mucinous metaplasia involving Warthin tumor: three case reports

Zhao Haowei(), Han Qi, Sun Xiaoqin, Wang Yun, Chen Yu()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Pathology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2020-11-17 Revised:2021-03-19 Online:2022-02-01 Published:2022-02-07
  • Contact: Chen Yu E-mail:ZhaoHaowei95@hotmail.com;chen_yu55@hotmail.com

摘要:

Warthin样黏液表皮样癌是一种新近发现的涎腺黏液表皮样癌亚型,形态类似于Warthin瘤,但具有与黏液表皮样癌相似的t(11;19)(q21;p13)染色体易位。因此鉴别诊断非常重要。Warthin瘤合并黏液表皮样癌极为罕见。本文报告了1例Warthin样黏液表皮样癌、1例Warthin瘤合并黏液表皮样癌、1例Warthin瘤伴黏液化生,并讨论了Warthin瘤与黏液表皮样癌之间的可能联系。

关键词: 黏液表皮样癌, Warthin瘤, 化生, 涎腺

Abstract:

Warthin-like mucoepidermoid carcinoma (MEC) is a recently identified MEC variant of the salivary gland. MEC morphologically mimics Warthin tumor (WT) but harbors the same chromosomal translocation t (11; 19) (q21; p13) as MEC. Thus, differential diagnosis is crucial. MEC involving WT is extremely rare in salivary glands. In this study, we reported a case of Warthin-like MEC, a case of MEC co-existing with WT, and a case of mucinous metaplasia in WT. We also discussed the possible link between WT and MEC.

Key words: mucoepidermoid carcinoma, Warthin tumor, metaplasia, salivary gland

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