涎腺腺样囊性癌伴肺转移的治疗方案及预后

doi:10.7518/hxkq.2019.02.015

华西口腔医学杂志 ›› 2019, Vol. 37 ›› Issue (2): 214-219.doi: 10.7518/hxkq.2019.02.015

涎腺腺样囊性癌伴肺转移的治疗方案及预后

苏文^1,²,杨宏宇^1,²()

1.安徽医科大学口腔医学系,合肥 230032
2.北京大学深圳医院口腔颌面外科,深圳 518036

收稿日期:2018-07-30 修回日期:2018-10-20 出版日期:2019-04-01 发布日期:2019-04-28
通讯作者: 杨宏宇 E-mail:hyyang192@hotmail.com
作者简介:苏文,硕士,E-mail： 2440647189@qq.com
基金资助:
国家自然科学基金(81572654);深圳市创新委员会基础研究计划(JCYJ20150403091443303);深圳市创新委员会基础研究计划(JCYJ20150403091443286);深圳市创新委员会基础研究计划(JCYJ2016042873933559);深圳市创新委员会基础研究计划(SZBC2017023);深圳市三名工程项目(SZSM201512036)

Treatment plan and prognosis of salivary adenoid cystic carcinoma with lung metastasis

Wen Su^1,²,Hongyu Yang^1,²()

1.Dept. of Stomatology, Anhui Medical University, Hefei 230032, China
2.Dept. of Oral and Maxillofacial Surgery, Shenzhen Hospital, Peking University, Shenzhen 518036, China

Received:2018-07-30 Revised:2018-10-20 Online:2019-04-01 Published:2019-04-28
Contact: Hongyu Yang E-mail:hyyang192@hotmail.com
Supported by:
The National Natural Science Foundation of China(81572654);The Basic Research Program of Shenzhen Innovation Council(JCYJ20150403091443303);The Basic Research Program of Shenzhen Innovation Council(JCYJ20150403091443286);The Basic Research Program of Shenzhen Innovation Council(JCYJ2016042873933559);The Basic Research Program of Shenzhen Innovation Council(SZBC2017023);Sanming Project of Medicine in Shenzhen(SZSM201512036)

摘要/Abstract

摘要：

涎腺腺样囊性癌（SACC）是口腔颌面部常见的恶性肿瘤之一,约占头颈部恶性肿瘤的3%~5%,最常发生于腭部小唾液腺及腮腺。该肿瘤浸润性强,呈现嗜神经侵袭、高血行性转移、低淋巴结转移等生物学特性,这些特性决定了其临床治疗的特殊性。SACC伴肺转移的系统性研究报道较为罕见,远期疗效不佳,治疗方案尚未达成共识。本综述的目的是回顾并总结SACC伴肺转移的治疗方案及预后,为其临床治疗提供依据。

关键词: 涎腺腺样囊性癌, 肺转移, 临床治疗

Abstract:

Salivary adenoid cystic carcinoma (SACC) is a common malignant tumor in the oral and maxillofacial region and accounts for approximately 3%-5% of all head and neck carcinomas. SACC always occurs in the palatal salivary gland and parotid gland. The tumor has the characteristics of strong invasion, perineural invasion, high hematogenous metastasis, and low lymph node metastasis rate. The biological characteristics of SACC determine the specificity of clinical treatment. Thus far, few clinical trials have investigated the efficacy of systemic therapy owing to the rarity of SACC with lung metastasis. Moreover, long-term results are poor, and no consensus on standard treatment has been reached yet. This systematic review aims to provide a retrospective analysis of treatment options and prognosis for SACC with lung metastasis and evidence for future clinical treatment.

Key words: salivary adenoid cystic carcinoma, lung metastatic, clinical treatment

中图分类号:

R739.8

苏文,杨宏宇. 涎腺腺样囊性癌伴肺转移的治疗方案及预后[J]. 华西口腔医学杂志, 2019, 37(2): 214-219.

Wen Su,Hongyu Yang. Treatment plan and prognosis of salivary adenoid cystic carcinoma with lung metastasis[J]. West China Journal of Stomatology, 2019, 37(2): 214-219.

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涎腺腺样囊性癌伴肺转移的治疗方案及预后

Treatment plan and prognosis of salivary adenoid cystic carcinoma with lung metastasis

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