华西口腔医学杂志

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生物活性玻璃改性树脂粘接剂对牙本质脱矿及树脂粘接强度的影响

王瑜  龚玲  计艳  郑丽纯  陈嵩   

  1. 南京大学医学院附属口腔医院预防口腔科,南京 210008
  • 出版日期:2016-08-01 发布日期:2016-08-01
  • 通讯作者: 龚玲,主任医师,学士,E-mail:glinnanjing@hotmail.com
  • 作者简介:王瑜,主治医师,硕士,E-mail:wangyunjmu1981@sina.com
  • 基金资助:

    南京市医学科技发展项目(YKK14111)

Effects of dentin demineralization and bond-strength properties of bioactive glass containing resin adhesive

Wang Yu, Gong Ling, Ji Yan, Zheng Lichun, Chen Song   

  1. Dept. of Preventive Dentistry, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing 210008, China
  • Online:2016-08-01 Published:2016-08-01
  • Contact: Gong Ling, E-mail: glinnanjing@hotmail.com
  • Supported by:

    Nanjing Medical Science and Technology Development Program (YKK14111)

摘要:

目的  研究生物活性玻璃(BG)改性树脂粘接剂抑制牙本质脱矿及对树脂-牙本质微拉伸粘接强度的影响。方法  将硅烷偶联剂表面处理后的BG与Single Bond 2粘接剂混合制备出30%、40%和50%的BG改性的树脂粘接剂,选择上颌前磨牙40颗,随机分为4组,阴性对照组(不添加BG)、30%BG组、40%BG组、50%BG组,每组10颗。根据分组分别采用相应BG含量的粘接剂制备树脂-牙本质粘接试件。将制备的粘接试件在37 ℃水浴中浸泡24 h后进行微拉伸粘接强度测试。每组选择1个牙片浸泡在pH 4.0的人工唾液中1周,每24 h测试溶液的pH值。结果  阴性对照组、30%BG组、40%BG组、50%BG组的粘接强度分别为(27.76±0.29)、(27.05±0.58)、(26.95±0.69)和(25.12±0.24)MPa。对照组和30%BG组的粘接强度无统计学差异(P=0.06),和40%BG组、50%BG组有统计学差异(P=0.04,P=0.00);30%、40%BG组的粘接强度高于50%BG组(P=0.00,P=0.00)。随着BG含量的增加,pH值也逐渐增高。结论  含有BG的树脂粘接剂可以有效抑制牙本质的脱矿,30%BG组对短期的粘接强度无明显影响,50%BG组抑制脱矿能力最强,但是粘接强度较低。

关键词: 生物活性玻璃, 树脂粘接剂, 牙本质, pH值, 粘接强度

Abstract:

Objective  This study investigated the shear bond strength and the ability of resin adhesive containing different amounts of bioactive glass (BG) to prevent dentin demineralization. Methods  BG bonds at 30%, 40%, and 50% concentrations comprised a mixture of coupling agents modifying BG and Single Bond 2. Forty permanent premolars extracted for orthodontic treatment were randomly divided into four groups, namely, control group (BG-free), 30% BG group, 40% BG group, and 50% BG group. Composite resin and dentin were prepared into bonding specimens by using respective adhesives and then immersed in artificial saliva at pH 4 for 1 week. Changes in the pH values of the solution were measured every 24 h. The microtensile bond strength (TBS) of each specimen was examined after immersion in distilled water at 37 °C for 24 h. Results  The TBS values of the control group, 30% BG group, 40% BG group, and 50% BG group were (27.76±0.29), (27.05±0.58), (26.95±0.69), and (25.12±0.24) MPa, respectively. The TBS of the control group was not significantly different from that of the 30% BG group (P=0.06) but significantly higher than that of the 40% BG and 50% BG groups (P=0.04 and P=0.00, respectively). In addition, TBS was significantly higher in the 30% BG and 40% BG groups than in the 50% BG group (P= 0.00 and P=0.00, respectively). The pH values of the solution increased with increasing BG content. Conclusion  BG bonds are useful in the prevention of dentin demineralization. However, in this study, the 30% BG group did not affect the shortterm bond strength. The 50% BG group displayed the optimum ability to inhibit demineralization but showed the worst bond strength.

Key words: bioactive glass, resin adhesive, dentin, pH value,  bond strength