华西口腔医学杂志 ›› 2020, Vol. 38 ›› Issue (4): 460-463.doi: 10.7518/hxkq.2020.04.019

• 病例报告 • 上一篇    下一篇

种植体引起双膦酸盐相关性下颌骨坏死1例

吴平凡(), 李羽, 雷振革, 陈林林()   

  1. 南昌大学附属口腔医院 江西省口腔生物医学重点实验室,南昌 330006
  • 收稿日期:2019-08-25 修回日期:2020-03-19 出版日期:2020-08-01 发布日期:2020-08-03
  • 通讯作者: 陈林林 E-mail:oral_surgery@sina.com
  • 作者简介:吴平凡,主治医师,硕士,E-mail: wupingfankq@163.com
  • 基金资助:
    江西省卫生计生委科技计划(20171096)

Bisphosphonate-related osteonecrosis of the jaw caused by implant: a case report

Wu Pingfan(), Li Yu, Lei Zhenge, Chen Linlin()   

  1. Affiliated Stomatological Hospital of Nanchang University, The Key Laboratory of Biomedicine of Jiangxi Province, Nanchang 330006, China
  • Received:2019-08-25 Revised:2020-03-19 Online:2020-08-01 Published:2020-08-03
  • Contact: Chen Linlin E-mail:oral_surgery@sina.com
  • Supported by:
    Science and Technology Plan of Health Commission of Jiangxi Province(20171096)

摘要:

随着双膦酸盐类药物在骨质疏松、恶性肿瘤骨转移等方面的广泛应用,不断有颌骨坏死发生的报道,已逐渐引起口腔医生的高度关注。本文报道1例种植体植入术后引起双膦酸盐相关性颌骨坏死的病例,并结合相关文献阐述双膦酸盐类药物性颌骨坏死的发病机制、诊断、预防及治疗方法,进一步讨论使用双膦酸盐后对种植体的影响。

关键词: 双膦酸盐, 骨坏死, 颌骨, 种植体

Abstract:

Osteonecrosis of the jaw could occur after intake of bisphosphonate drugs, which are widely used to treat osteoporosis and bone metastasis of malignant tumors. This effect has aroused concern among dentists. In this paper, a case of bisphosphonate-related osteonecrosis caused by implant is reported, and the pathogenesis, diagnosis, prevention, and treatment of bisphosphonate drug-induced osteonecrosis are described through a literature review. The effects of bisphosphonate drug treatment on dental implants are also discussed.

Key words: bisphosphonate, osteonecrosis, jaw, implant

中图分类号: