系统性药物对种植体骨结合影响的动物实验研究进展

doi:10.7518/hxkq.2020.02.017

华西口腔医学杂志 ›› 2020, Vol. 38 ›› Issue (2): 211-217.doi: 10.7518/hxkq.2020.02.017

系统性药物对种植体骨结合影响的动物实验研究进展

王亚楠¹^,², 贾婷婷¹^,², 徐欣¹^,²^,³, 张东姣¹^,²^,³()

^1. 山东大学口腔医学院,济南 250012
^2. 山东省口腔组织再生重点实验室
^3. 山东大学口腔医院种植中心,济南 250012

收稿日期:2019-06-05 修回日期:2019-08-25 出版日期:2020-04-01 发布日期:2020-04-15
通讯作者: 张东姣 E-mail:djzhang1109@163.com
作者简介:王亚楠,博士,E-mail：1152978529@qq.com
基金资助:
泰山学者建设工程专项经费(TS201511106);中国博士后科学基金第61批面上资助项目(21350077311085);博士后日常经费资助项目(10000087962028)

Overview of animal researches about the effects of systemic drugs on implant osseointegration

Wang Ya’nan¹^,², Jia Tingting¹^,², Xu Xin¹^,²^,³, Zhang Dongjiao¹^,²^,³()

^1. School of Stomatology, Shandong University, Jinan 250012, China
^2. Shandong Provincial Key Laboratory of Oral Tissue Regeneration, Jinan 250012, China
^3. Dept. of Implantology, Stomatological Hospital of Shandong University, Jinan 250012, China

Received:2019-06-05 Revised:2019-08-25 Online:2020-04-01 Published:2020-04-15
Contact: Dongjiao Zhang E-mail:djzhang1109@163.com
Supported by:
Special Funds for Taishan Scholars(TS201511106);The 61st Batch of China Postdoctoral Science Foundation(21350077311085);Postdoctoral Daily Funds(10000087962028)

摘要/Abstract

摘要：

种植体周围骨结合是口腔种植重要的生物学基础。影响种植体骨结合的因素繁多,包括手术因素、种植体因素、患者自身因素等,其中应用系统性药物以改善种植体骨结合的相关研究已经成为当今的研究热点。本文基于动物实验研究,对系统性药物影响种植体骨结合的作用进行综述,以期为改善种植体骨结合提供可供选择的高效安全的系统性药物,为后期临床试验的开展奠定基础。

关键词: 种植体, 骨结合, 系统性药物, 动物实验

Abstract:

Implant osseointegration is an important biological basis for dental implantology. Many factors, including surgical factors, implant factors, and patients’ own factors, affect implant osseointegration. Notably, the application of systemic drugs to improve implant osseointegration has become a research hotspot. This article reviews the effects of systemic drugs on implant osseointegration based on animal researches to provide systemic drug selection to improve implant osseointegration and lay a good foundation for later clinical trials.

Key words: implant, osseointegration, systemic drugs, animal researches

中图分类号:

R783

王亚楠, 贾婷婷, 徐欣, 张东姣. 系统性药物对种植体骨结合影响的动物实验研究进展[J]. 华西口腔医学杂志, 2020, 38(2): 211-217.

Wang Ya’nan, Jia Tingting, Xu Xin, Zhang Dongjiao. Overview of animal researches about the effects of systemic drugs on implant osseointegration[J]. West China Journal of Stomatology, 2020, 38(2): 211-217.

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系统性药物对种植体骨结合影响的动物实验研究进展

Overview of animal researches about the effects of systemic drugs on implant osseointegration

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