华西口腔医学杂志 ›› 2019, Vol. 37 ›› Issue (5): 547-550.doi: 10.7518/hxkq.2019.05.018

• 综述 • 上一篇    下一篇

影响非综合征型唇腭裂的环境因素

陆铖,王江玥,贾仲林()   

  1. 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心四川大学华西口腔医院唇腭裂外科,成都 610041
  • 收稿日期:2019-03-05 修回日期:2019-08-02 出版日期:2019-10-01 发布日期:2019-10-15
  • 通讯作者: 贾仲林 E-mail:zhonglinjia@sina.com
  • 作者简介:陆铖,学士,E-mail:i.luchen@foxmail.com

Environmental factors of non-syndromic cleft lip and palate

Lu Cheng,Wang Jiangyue,Jia Zhonglin()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cleft Lip and Palate Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2019-03-05 Revised:2019-08-02 Online:2019-10-01 Published:2019-10-15
  • Contact: Zhonglin Jia E-mail:zhonglinjia@sina.com

摘要:

非综合征型唇腭裂的发生机制目前尚未完全明确,但该疾病受环境与遗传的共同影响,特殊的环境因素可能加大或降低患儿唇腭裂的发生率。本文对非综合征型唇腭裂发生有关的环境因素从孕期不良生活习惯、化学因素、孕妇年龄及健康状况三大方面总结分析了可能增加唇腭裂发生的多个环境因素,以有助于改善孕妇健康情况及生活环境,从而达到降低唇腭裂患病率的目的。

关键词: 唇腭裂, 环境因素, 孕妇健康状况

Abstract:

Though the mechanism of non-syndromic cleft lip and palate is not completely clear, the disease is affected by the combination of environment and genetics. Special environmental factors have the affect on the incidence of cleft palate. In this paper, the environmental factors related to the occurrence of non-syndromic cleft lip and palate were summarize from three aspects: poor living habits, chemical factors, age and health status of pregnant women during pregnancy. Based on the analysis of this paper, it will help to improve the health and living environment of pregnant women, so as to reduce the incidence of cleft palate.

Key words: cleft lip and palate, environmental factors, pregnant women’s health;

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