华西口腔医学杂志 ›› 2015, Vol. 33 ›› Issue (6): 656-659.doi: 10.7518/hxkq.2015.06.022

• 综述 • 上一篇    下一篇

牙髓干细胞在组织工程领域的研究进展

史诗彧,谢家敏   

  1. 南通大学附属第五医院口腔科,泰州 225300
  • 收稿日期:2015-04-26 修回日期:2015-09-23 出版日期:2015-12-01 发布日期:2015-12-01
  • 通讯作者: 谢家敏,主任医师,博士,E-mail:xiejiamin1101@163. com
  • 作者简介:史诗彧,硕士,E-mail:shishiyu0419@163.com

Study progress of dental pulp stem cells in tissue engineering

Shi Shiyu, Xie Jiamin   

  1. Dept. of Stomatology, The Fifth Affiliated Hospital of Nantong University, Taizhou 225300, China)
  • Received:2015-04-26 Revised:2015-09-23 Online:2015-12-01 Published:2015-12-01

摘要: 种子细胞的获得、培养与分化是组织工程的前提和基础,将干细胞作为种子细胞用于组织工程的构建受到越来越多学者的关注。牙髓干细胞(DPSCs)是存在于牙髓组织中的一种成体干细胞,是一种新兴的组织工程种子细胞,对于组织器官的再生具有重要的意义。本文就牙髓干细胞在组织工程的研究现状作一综述,并对其临床应用前景进行讨论。

关键词: 牙髓干细胞, 多向分化, 组织工程, 应用前景

Abstract: In recent years, modern tissue engineering is becoming emerging and developing rapidly, and the acquisition, cultivation and differentiation of seed cells is the premise and foundation of the construction of tissue engineering, so more and more scholars pay attention to stem cells as seed cells for tissue engineering construction. Dental pulp stem cells (DPSCs) is a kind of adult stem cells derived from dental pulp, and as a new kind of seed cells of tissue engineering, the study of DPSCs presents important significance in tissue and organ regeneration. In this review, we introduced the progress of studies on dental pulp stem cells and discussed their clinical application prospects.

Key words: dental pulp stem cells, multiple differentiation, tissue engineering, application prospect

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