华西口腔医学杂志

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股前外侧肌皮瓣及CT血管造影在修复中晚期口底癌术后缺损中的应用

罗世洪1  肖金刚1,2  孙黎波1  张力1  曾梁楠3  夏德林1  周航宇1  张磊1   

  1. 1.泸州医学院附属口腔医院口腔颌面外科;2.口颌面修复重建和再生实验室;
    3.泸州医学院附属医院神经外科,泸州 646000
  • 出版日期:2015-08-01 发布日期:2015-08-01
  • 通讯作者: 肖金刚,副教授,博士,E-mail:drxiaojingang@163.com
  • 作者简介:罗世洪,硕士,E-mail:15228281144@163.com
  • 基金资助:

    国家自然科学基金资助项目(81371125);四川省科技厅基金资助项目(2014JY0044);四川省教育厅基金资助项目(10ZB030)

Application of anterolateral thigh myocutaneous flap using computed tomography angiography for mouth-floor reconstruction after resection of middle-late stage carcinoma of mouth floor

 Luo Shihong1, Xiao Jingang1,2, Sun Libo1, Zhang Li1, Zeng Liangnan3, Xia Delin1, Zhou Hangyu1, Zhang Lei1   

  1. 1. Dept. of Oral and Maxillofacial Surgery, Hospital of Stomatology, Luzhou Medical College, Luzhou 646000, China; 2. Orofacial Reconstruction and Regeneration Laboratory, Hospital of Stomatology, Luzhou Medical College, Luzhou 646000, China; 3. Dept. of Neurosurgery, Affiliated Hospital, Luzhou Medical College, Luzhou 646000, China
  • Online:2015-08-01 Published:2015-08-01

摘要:

目的 探讨游离股前外侧肌皮瓣在中晚期口底癌术后缺损修复重建中的治疗效果及CT血管造影(CTA)定位股前外侧肌皮瓣穿支血管的应用价值。方法 对16例中晚期口底癌患者在施行口底癌根治性切除术同时运用游离股前外侧肌皮瓣行软组织缺损的修复重建,术前应用CTA定位旋股外侧动脉及穿支血管。结果 16例患者术前CTA定位的穿支血管与术中所见完全吻合,股前外侧肌皮瓣移植手术均获成功。术后随访6~36个月,患者的口底、舌外形恢复良好,张口度理想,吞咽及语言功能满意,供区无明显后遗症,肿瘤局部无复发,其中1例患者(T4N2M0期)在术后10个月因发生远处转移而死亡。结论 CTA能精确定位旋股外侧动脉及穿支血管,游离股前外侧肌皮瓣是修复重建中晚期口底癌术后组织缺损的理想选择。

关键词: 口底癌, 缺损, CT血管造影, 股前外侧肌皮瓣, 修复重建

Abstract:

Objective The aim of this study was to investigate the value of free anterolateral thigh myocutaneous flap (ALTMF) and computed tomography angiography (CTA) for the reconstruction of mouth-floor defects after the resection of middle-late stage carcinoma of the mouth floor. Methods Sixteen cases of middle-late stage carcinomas of the mouth floor underwent radical resection, and mouth-floor and tongue defects were reconstructed with ALTMF. CTA was applied to plan the lateral circumflex femoral artery (LCFA) and its perforating vessel, which was verified during the operation. Results The position of the perforating vessel in the operation was fully consistent with that designed by the preoperative CTA. All 16 flaps completely survived. The appearance and function of all cases were both satisfactory. All donor sites were primarily closed and healed without functional morbidity. During the follow-up period of 6–36 months, 15 cases survived with acceptable aesthetic and functional results in mouth floor and tongue reconstruction, except for 1 case (T4N2M0) that died of metastasis carcinoma 10 months after operation. Conclusion CTA can accurately locate the LCFA and artery perforator. Preoperative perforator planning using CTA in ALTMF transplantation is a reliable and useful method thatresults in safe operation with optimal outcome. The ALTMF is an ideal choice for the reconstruction of soft tissue defects after the resection of middle-late stage carcinoma of the mouth floor.

Key words: carcinoma of mouth floor, defect, computed tornography angiography, anterolateral thigh myocutaneous flap, reconstruction