关键词: 口腔微生物组, 基因芯片, 第二代测序, 宏基因组

Abstract:

The human resident microorganisms constitute the second genome of human body. Oral microbiome is closely related to the oral and systemic health and diseases. Implementation of high-throughput gene chip and second- generation sequencing has gained in-depth characterization of the oral microbiome, changing our view on host-microbe interactions. In this review, we summarized the latest progress in oral microbial metagenomics and addressed its potential value in the prevention and treatment of oral diseases and other systemic disorders.

Key words: oral microbiome, gene chip, second-generation sequencing, metagenomics