华西口腔医学杂志

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人体口腔微生物群的相互作用

施文元1 周学东2   

  1. 1.美国加州大学洛杉矶分校牙学院, 美国洛杉矶CA 90045;2.口腔疾病研究国家重点实验室, 四川大学, 四川成都610041
  • 收稿日期:2010-02-25 修回日期:2010-02-25 出版日期:2010-02-20 发布日期:2010-02-20
  • 通讯作者: 周学东,Tel:028-85501481
  • 作者简介:施文元(1962—),男,浙江人,教授,博士

Interaction of human oral microbial community

SHI Wen-yuan1, ZHOU Xue-dong2   

  1. 1. School of Dentistry, University of California, Los Angeles, CA 90045, USA; 2. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China
  • Received:2010-02-25 Revised:2010-02-25 Online:2010-02-20 Published:2010-02-20
  • Contact: ZHOU Xue-dong,Tel:028-85501481

摘要:

人体微生物群是一个极其复杂的生态系,其中尤以口腔微生物群为典型代表。不同的人体口腔微生物群不同,同一个体口腔不同部位、同一部位不同时间的口腔微生物群的分布也不相同。这种微生物群组成和变化的多样性决定了人体口腔生态系的平衡与失调,决定着口腔疾病的发生与发展。本文重点介绍人体口腔微生物群的研究历史和最新进展。

关键词: 口腔微生物群, 发病机制, 代谢

Abstract:

Human body is inhabited by large number of microbial organisms that form complex ecosystems. Oral cavity is one of the major sites for microbial colonization. Oral microbial diversity is huge as the compositions vary among different oral cavities, different locations within the same oral cavity, or same location at different time points. The differences in compositions and varieties determine the balance of human oral microbial ecosystem, which is directly associated with oral disease or health. This review focuses on the history and new progress of the studies on human oral microbial communities.

Key words: oral microbial community, pathogenesis, metabolism